Pregnancy Outcomes in Congenital Myasthenie Syndrome (POCoMS)
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ClinicalTrials.gov Identifier: NCT01474980
Recruitment Status :
First Posted : November 18, 2011
Last Update Posted : November 18, 2011
Institut de Myologie, France
Assistance Publique - Hôpitaux de Paris
Information provided by (Responsible Party):
Laurent Servais, M.D., Institut de Myologie, France
This is a retrospective study that follows the clinical evolution, the pregnancy and the post-partum perioad of female patients with Congenital Myasthenic Syndrome.
Condition or disease
Congenital Myasthenic Syndrome
The aim of this study is to better understand the action of hormonal factors that are presumably incriminated for the fluctuation of the disease. The investigators would also like to better adress the issues of women with Congenital Myasthenic Syndrome, who desire a pregnancy : the possibility of decompensation, the problems that can arise during the course of the childbearing, the risk of foetal malformations.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Women with Congenital Myasthenie Syndrome
Congenital myastenic syndrome genetically confirmed or with clinical compatible and electrophysiological evidence
Neurological or general pathology occurs significantly with the initiation and conduct of a pregnancy.