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Venous Function in Cardiovascular Disease Patients

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ClinicalTrials.gov Identifier: NCT01474408
Recruitment Status : Completed
First Posted : November 18, 2011
Last Update Posted : February 14, 2017
Sponsor:
Information provided by (Responsible Party):
Norwegian University of Science and Technology

Brief Summary:
The primary aim is to determine the acute effect of two different training interventions on venous plasticity in patients with myocardial infarction (MI), revascularization or coronary artery graft surgery compared to age-matched healthy subjects.

Condition or disease Intervention/treatment
Myocardial Infarction Behavioral: interval training day 1 Behavioral: Moderate exercise day 2 Behavioral: Control day 3

Detailed Description:
Compare the effect of 4 x 4 minutes at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate and moderate continuous exercise at 70 % of peak heart rate on venous function.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 10 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Investigator)
Primary Purpose: Treatment
Official Title: Venous Function in Cardiovascular Disease Patients; The Neglected Part of Circulatory Regulation
Study Start Date : November 2011
Primary Completion Date : November 2012
Study Completion Date : November 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Heart Attack
U.S. FDA Resources

Arm Intervention/treatment
Experimental: interval training
4 x 4 minutes exercise at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate
Behavioral: interval training day 1
Other Name: aerobic interval training
Behavioral: Moderate exercise day 2 Behavioral: Control day 3
Active Comparator: moderate exercise
moderate continuous exercise at 70 % of peak heart rate on venous function.
Behavioral: interval training day 1
Other Name: aerobic interval training
Behavioral: Moderate exercise day 2 Behavioral: Control day 3
control
routine measurements, no exercise
Behavioral: interval training day 1
Other Name: aerobic interval training
Behavioral: Moderate exercise day 2 Behavioral: Control day 3



Primary Outcome Measures :
  1. Venous Compliance change [ Time Frame: 48 hours ]
    Measured by echocardiography



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • myocardial infraction (MI)
  • revascularization (PCI)
  • coronary artery bypass graft surgery (CABG)

Exclusion Criteria:

  • unstable angina pectoris
  • uncontrolled hypertension
  • orthopedic and/or neurological limitations
  • participation in other studies
  • MI (closer than 4 weeks)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01474408


Locations
Norway
Institutt for Sirkulasjon og Bildetechnikk, NTNU
Trondheim, Norway
Sponsors and Collaborators
Norwegian University of Science and Technology
Investigators
Study Director: Ulrik Wisløff, prof Norwegian University of Science and Technology

Publications:
Responsible Party: Norwegian University of Science and Technology
ClinicalTrials.gov Identifier: NCT01474408     History of Changes
Other Study ID Numbers: 2011/760
First Posted: November 18, 2011    Key Record Dates
Last Update Posted: February 14, 2017
Last Verified: February 2017

Keywords provided by Norwegian University of Science and Technology:
Coronary artery bypass
Exercise therapy
Revascularization (PCI)

Additional relevant MeSH terms:
Infarction
Cardiovascular Diseases
Myocardial Infarction
Ischemia
Pathologic Processes
Necrosis
Myocardial Ischemia
Heart Diseases
Vascular Diseases