Comparison of Intubation Duration Between Rapid Sequence Intubation (RSI) Technique and Non-RSI Technique
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|ClinicalTrials.gov Identifier: NCT01474252|
Recruitment Status : Completed
First Posted : November 18, 2011
Last Update Posted : June 2, 2016
|Condition or disease||Intervention/treatment||Phase|
|Tracheal Intubation Morbidity||Drug: RSI||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||224 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Comparison of Intubation Duration Between Rapid Sequence Intubation Technique and Non- Rapid Sequence Intubation Technique in Siriraj Hospital by Emergency Medicine Residences|
|Study Start Date :||July 2008|
|Primary Completion Date :||December 2012|
|Study Completion Date :||December 2013|
Experimental: RSI technique
Intubation with RSI technique. RSI technique includes the administration of inductive and neuromuscular blocking agents to facilitate an intubation.
In this study, we have no restriction of medication use. Physicians can chose any of medication as an individual judgement.
All medications are administered only one dose before intubation
Propofol 2-2.5 mg/kg Thiopental 3-5mg/kg Etomidate 1-2mg/kg
Neuromuscular blocking agents:
Succinylcholine 1-1.5mg/kg Rocuronium 0.9mg/kg
Other Name: Rapid Sequence Intubation
No Intervention: Non-RSI
Intubation without RSI technique. No any medication use during intubation period.
- The overall intubation duration [ Time Frame: Participants will be followed for the overall intubation duration until confirmation the endotracheal position, an expected average of 2 minutes ]The overall intubation duration is recorded on the decision to intubation patient and corresponds to the time of confirmation the endotracheal position by chest auscultation
- the intubation duration [ Time Frame: Participants will be followed for the intubation duration until confirmation the endotracheal position, an expected average of 5 minutes ]The intubation duration (Ti), it is defined from application the laryngoscope into the patient's mouth to the time of confirmation an endotracheal position
- Complication [ Time Frame: Participants will be followed in the period of staying in the emergency room and hospital, an expected average of 4 weeks ]Complications occur during and after intubation peroid are recorded and monitored until patients are discharged fromt the hospital.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01474252
|Bangkok, Thailand, 10700|
|Principal Investigator:||Mingkwan Wongyingsinn, M.D.||Siriraj Hospital|