Comparison of Intubation Duration Between Rapid Sequence Intubation (RSI) Technique and Non-RSI Technique
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
|Official Title:||Comparison of Intubation Duration Between Rapid Sequence Intubation Technique and Non- Rapid Sequence Intubation Technique in Siriraj Hospital by Emergency Medicine Residences|
- The overall intubation duration [ Time Frame: Participants will be followed for the overall intubation duration until confirmation the endotracheal position, an expected average of 2 minutes ] [ Designated as safety issue: No ]The overall intubation duration is recorded on the decision to intubation patient and corresponds to the time of confirmation the endotracheal position by chest auscultation
- the intubation duration [ Time Frame: Participants will be followed for the intubation duration until confirmation the endotracheal position, an expected average of 5 minutes ] [ Designated as safety issue: No ]The intubation duration (Ti), it is defined from application the laryngoscope into the patient's mouth to the time of confirmation an endotracheal position
- Complication [ Time Frame: Participants will be followed in the period of staying in the emergency room and hospital, an expected average of 4 weeks ] [ Designated as safety issue: Yes ]Complications occur during and after intubation peroid are recorded and monitored until patients are discharged fromt the hospital.
|Study Start Date:||July 2008|
|Study Completion Date:||December 2013|
|Primary Completion Date:||December 2012 (Final data collection date for primary outcome measure)|
Experimental: RSI technique
Intubation with RSI technique. RSI technique includes the administration of inductive and neuromuscular blocking agents to facilitate an intubation.
In this study, we have no restriction of medication use. Physicians can chose any of medication as an individual judgement.
All medications are administered only one dose before intubation
Propofol 2-2.5 mg/kg Thiopental 3-5mg/kg Etomidate 1-2mg/kg
Neuromuscular blocking agents:
Succinylcholine 1-1.5mg/kg Rocuronium 0.9mg/kg
Other Name: Rapid Sequence Intubation
No Intervention: Non-RSI
Intubation without RSI technique. No any medication use during intubation period.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01474252
|Bangkok, Thailand, 10700|
|Principal Investigator:||Mingkwan Wongyingsinn, M.D.||Siriraj Hospital|