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A Study of Flt3-Ligand Levels in Sjögrens Syndrome

This study is currently recruiting participants.
Verified July 2017 by Göteborg University
Sponsor:
ClinicalTrials.gov Identifier:
NCT01470638
First Posted: November 11, 2011
Last Update Posted: July 5, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Information provided by (Responsible Party):
Göteborg University
  Purpose
The study aims to correlate levels of Flt3-ligand in Cerebrospinal Fluid (CSF) and serum to markers for inflammation and degeneration in patients with primary Sjogrens syndrome.

Condition
Sjogrens Syndrome

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Analyzes of Cerebrospinal Fluid in Autoimmune Systemic Diseases

Resource links provided by NLM:


Further study details as provided by Göteborg University:

Primary Outcome Measures:
  • Correlate levels of Flt3-ligand in Cerebrospinal Fluid (CSF) and serum to markers for inflammation and degeneration in patients with primary Sjogrens syndrome [ Time Frame: June 2009 - June 2015 ]

Biospecimen Retention:   Samples Without DNA
Serum, cerebrospinal fluid

Estimated Enrollment: 50
Study Start Date: June 2009
Estimated Study Completion Date: December 2017
Estimated Primary Completion Date: December 2017 (Final data collection date for primary outcome measure)
Detailed Description:
The study aims to correlate levels of Flt3-ligand in CSF and serum to markers for inflammation and degeneration in patients with primary Sjogrens syndrome.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
The rheumatology clinic at Sahlgrenska University hospital, Gothenburg, Sweden
Criteria

Inclusion Criteria:

  • fulfill the ACR-criteria for primary Sjogrens syndrome,
  • age above 18 years old

Exclusion Criteria:

  • other CNS-disease
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01470638


Contacts
Contact: Mats Dehlin, PhD-student +46-31-3424173 mats.dehlin@vgregion.se

Locations
Sweden
Dept of Rheumatology, Sahlgrenska University Hospital Recruiting
Gothenburg, Sweden, 413 46
Contact: Mats Dehlin, PhD student    +46-31-3424173    mats.dehlin@vgregion.se   
Principal Investigator: Mats Dehlin, MD         
Sponsors and Collaborators
Göteborg University
  More Information

Responsible Party: Göteborg University
ClinicalTrials.gov Identifier: NCT01470638     History of Changes
Other Study ID Numbers: Flt3-L SS
First Submitted: November 9, 2011
First Posted: November 11, 2011
Last Update Posted: July 5, 2017
Last Verified: July 2017

Keywords provided by Göteborg University:
Flt3-L
CSF

Additional relevant MeSH terms:
Sjogren's Syndrome
Syndrome
Disease
Pathologic Processes
Arthritis, Rheumatoid
Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Xerostomia
Salivary Gland Diseases
Mouth Diseases
Stomatognathic Diseases
Dry Eye Syndromes
Lacrimal Apparatus Diseases
Eye Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases