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Longitudinal Survey Analysis in Lymphoma Survivors (CLEAR Stress)

This study has been completed.
Information provided by (Responsible Party):
Weill Medical College of Cornell University Identifier:
First received: November 8, 2011
Last updated: May 1, 2014
Last verified: May 2014

Posttraumatic Stress Disorder (PTSD) is a well-documented phenomenon that occurs in cancer survivors. PTSD is known to cause problems with anxiety, depression, and quality of life. Furthermore, there is little treatment available for cancer survivors who suffer from PTSD.

Posttraumatic Growth, however, is a lesser known phenomenon that also occurs in cancer survivors. It is a positive psychological phenomenon that occurs in some people who have suffered a traumatic event--the people who are able to note a "greater appreciation for life", a "stronger relationship with their family/friends," or a "new found level of spirituality" are examples of instances of posttraumatic growth.

Coping with Lymphoma to Enhance Adjustment and Reduce Stress in Survivors (CLEAR Stress) is a study designed to compare the development of PTSD versus the development of Posttraumatic Growth in lymphoma patients at any stage of the cancer experience, regardless of treatment. The hypothesis is that posttraumatic growth, if it is significant, can reduce the impact of PTSD symptoms in the survivor.

Posttraumatic Stress Disorder
Posttraumatic Growth

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Coping With Lymphoma to Enhance Adjustment and Reduce Stress in Lymphoma Survivors

Resource links provided by NLM:

Further study details as provided by Weill Medical College of Cornell University:

Primary Outcome Measures:
  • Posttraumatic Growth [ Time Frame: Measured at enrollment ]

Secondary Outcome Measures:
  • Posttraumatic Stress Disorder (PTSD) [ Time Frame: Measured at Enrollment ]

Enrollment: 97
Study Start Date: September 2011
Study Completion Date: September 2013
Primary Completion Date: July 2013 (Final data collection date for primary outcome measure)
Lymphoma Survivors


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Lymphoma survivors who have completed initial treatment within the last 3 months

Inclusion Criteria:

  • Diagnosis of Lymphoma (includes Waldenstrom's Macroglobulinemia)
  • Can read/write/understand English without a translator

Exclusion Criteria:

  • Currently Hospitalized
  • Active Psychosis
  Contacts and Locations
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Please refer to this study by its identifier: NCT01469754

United States, New York
New York Presbyterian/Weill Cornell Center for Lymphoma and Myeloma
New York, New York, United States, 10065
Sponsors and Collaborators
Weill Medical College of Cornell University
Principal Investigator: Regina A Jacob, MD WCMC Research Fellow
  More Information

Additional Information:
Responsible Party: Weill Medical College of Cornell University Identifier: NCT01469754     History of Changes
Other Study ID Numbers: 1107011786
Study First Received: November 8, 2011
Last Updated: May 1, 2014

Keywords provided by Weill Medical College of Cornell University:
posttraumatic growth
posttraumatic stress

Additional relevant MeSH terms:
Stress Disorders, Post-Traumatic
Neoplasms by Histologic Type
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases
Stress Disorders, Traumatic
Trauma and Stressor Related Disorders
Mental Disorders processed this record on April 28, 2017