CMR Repeatability in STEMI

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01468662
Recruitment Status : Completed
First Posted : November 9, 2011
Last Update Posted : October 28, 2014
Information provided by (Responsible Party):
Elisa McAlindon, University of Bristol

Brief Summary:
The investigators propose to conduct a study to measure the reproducibility of CMR parameters that have been used to predict outcome following PPCI: infarct size, left ventricular volumes, myocardial salvage, microvascular obstruction (MVO) and myocardial oedema.

Condition or disease

Study Type : Observational
Actual Enrollment : 40 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Cardiovascular Magnetic Resonance Scan Repeatability in ST Segment Elevation Myocardial Infarction
Study Start Date : November 2011
Primary Completion Date : April 2013


Primary Outcome Measures :
  1. Inter-observer, intra-observer and inter-scan variability and agreement [ Time Frame: Between 2 scans ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
ST segment elevation myocardial infarction

Inclusion Criteria:

Participant may enter study if ALL of the following apply

  1. ST segment myocardial infarction as defined by ECG (by 2 contiguous limb leads with >1 mm ST-segment elevation, or >2 mm ST-segment elevation in contiguous precordial leads, or new LBBB) and > 20 minutes of cardiac chest pain
  2. Written informed consent

Exclusion Criteria:

Participant may not enter study if ANY of the following apply

  1. Contraindication to MRI (implanted pacemaker/ defibrillator, ferromagnetic metal implant/ injury, claustrophobia, obesity/ too large for CMR scanner)
  2. Known allergy to gadolinium
  3. Chronic atrial fibrillation
  4. Renal impairment with eGFR <30
  5. Cardiogenic shock
  6. Patients with special communication needs

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01468662

United Kingdom
Bristol Heart Institute
Bristol, United Kingdom, BS2 8HW
Sponsors and Collaborators
University of Bristol
Principal Investigator: Elisa McAlindon, BMBS University of Bristol

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Elisa McAlindon, Cardiology Clinical Research Fellow, University of Bristol Identifier: NCT01468662     History of Changes
Other Study ID Numbers: Study 1569
First Posted: November 9, 2011    Key Record Dates
Last Update Posted: October 28, 2014
Last Verified: October 2014

Additional relevant MeSH terms:
ST Elevation Myocardial Infarction
Myocardial Infarction
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases