Platelet Inhibition and Bleeding in Patients Undergoing Emergent Cardiac Surgery
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The aim of the study is to evaluate if there is an association between platelet inhibition and surgery-related bleeding in patients undergoing emergent cardiac surgery during dual antiplatelet therapy.
Condition or disease
Blood for measuring platelet function is drawn before induction of anesthesia
Calculated blood loss [ Time Frame: until postoperative day 5 ]
Secondary Outcome Measures :
BARC bleeding [ Time Frame: until postoperative day 2 ]
Intracranial bleed within 48 hours, Reoperation after closure of sternotomy for the purpose of controlling bleeding, Transfusion of equal to or more than 5 Units of packed red blood cells within a 48-hour period, Chest tube output of equal to or more than 2 L within a 24-h period.
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Ages Eligible for Study:
30 Years to 80 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients needing emergent cardiac surgery under dual antiplatelet therapy
First time on-pump CABG with or without valve replacement