Platelet Inhibition and Bleeding in Patients Undergoing Emergent Cardiac Surgery
The aim of the study is to evaluate if there is an association between platelet inhibition and surgery-related bleeding in patients undergoing emergent cardiac surgery during dual antiplatelet therapy.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Does Platelet Inhibition Predict Surgery Related Bleeding in Patients Undergoing Emergent Cardiac Surgery During Dual Antiplatelet Therapy - a Pilot Study|
- Calculated blood loss [ Time Frame: until postoperative day 5 ] [ Designated as safety issue: No ]
- BARC bleeding [ Time Frame: until postoperative day 2 ] [ Designated as safety issue: No ]Intracranial bleed within 48 hours, Reoperation after closure of sternotomy for the purpose of controlling bleeding, Transfusion of equal to or more than 5 Units of packed red blood cells within a 48-hour period, Chest tube output of equal to or more than 2 L within a 24-h period.
|Study Start Date:||January 2011|
|Study Completion Date:||August 2014|
|Primary Completion Date:||August 2014 (Final data collection date for primary outcome measure)|
Blood for measuring platelet function is drawn before induction of anesthesia
Please refer to this study by its ClinicalTrials.gov identifier: NCT01468597
|Department of Anesthesiology and Intensive Care Medicine, Department of Surgery, Medical University of Graz|
|Graz, Austria, 8036|
|Principal Investigator:||Elisabeth Mahla, M.D.||Department of Anesthesia and Intensive Care Medicine, Medical University of Graz|