Metacarpophalangeal Joint Reconstruction Using a Vascularized Cartilage and Bone Graft (MJRUVCBG)
Traumatic cartilage loss of the joint is central to the development of joint failure in arthritis. The study on the use of a bone graft for reconstruction of metacarpophalangeal joint defects.
Volar Plate Injury, Thumb, Metacarpophalangeal Joint
Procedure: MCP joint
|Study Design:||Endpoint Classification: Safety Study
Intervention Model: Single Group Assignment
Masking: Single Blind (Subject)
Primary Purpose: Treatment
|Official Title:||Phase 1 Study for Reconstruction of Metacarpophalangeal Joint Using a Vascularized Cartilage and Bone Graft From the Third Metacarpal|
- Range of motion; Arm, Shoulder and Hand questionnaire [ Time Frame: 4 years ] [ Designated as safety issue: Yes ]The active motions of the hand were measured by a goniometer. The patients rated their MCP joint pain, the donor joint pain, and scar pain using a line by a visual analogue scale (VAS). We used the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire to assess the hand function.
- Pain [ Time Frame: 4 years ] [ Designated as safety issue: Yes ]joint pain is assessed using visual analogue scale
|Study Start Date:||January 2005|
|Study Completion Date:||December 2009|
|Primary Completion Date:||January 2005 (Final data collection date for primary outcome measure)|
Experimental: MCP joint
reconstruction of metacarpophalangeal (MCP) joint
Procedure: MCP joint
reconstruction of metacarpophalangeal (MCP) joint using a bone graft
Other Name: MCP joint reconstruction
The metacarpophalangeal joint is vital for hand function. Cartilage loss of the joint is central to the development of joint failure in arthritis. Although various treatments have been proposed, the management remains a challenging problem.Previous anatomical studies have shown that, at the base of the metacarpal, there were nutrient arteries inserting into the dorsum of the metacarpal. The nutrient arteries arise from the distal and middle dorsal carpal arches that run distally to the first to fourth dorsal metacarpal arteries (DMAs. These studies prompt us to use a reverse vascularized cartilage and bone graft based on the DMA. The metacarpal consists of a widened proximal base. The joint surface to the capitate is convex anteriorly and dorsally concave, where it extends to the styloid process on the dorsolateral aspect of the metacarpal base. The unique contour stimulates our imagination and creativity to use a portion of the joint surface for reconstruction of metacarpophalangeal joint defects. The purpose of this study is to report the novel technique and to evaluate the effectiveness of the treatment.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01467752
|The second hospital of Qinhuangdao|
|Qinhuangdao, Hebei, China, 066600|
|Study Chair:||Xu Zhang, MD||The Second Hospital of Qinhuangdao|