University of Wisconsin hMSC Cell Bank: Bone Marrow Donor Protocol
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01463475|
Recruitment Status : Completed
First Posted : November 2, 2011
Last Update Posted : December 4, 2014
|Condition or disease||Intervention/treatment||Phase|
|Graft Versus Host Disease (GVHD) Acute Myocardial Infarction (AMI)||Procedure: Bone marrow aspirate||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||3 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||University of Wisconsin hMSC Cell Bank: Bone Marrow Donor Protocol|
|Study Start Date :||September 2011|
|Actual Primary Completion Date :||December 2013|
|Actual Study Completion Date :||December 2013|
Bone Marrow Aspirate
A qualified enrolled donor will have an aspirate bone marrow draw.
Procedure: Bone marrow aspirate
A single bone marrow aspirate procedure is planned.
Other Name: bone marrow-derived MSC
- Culture and expand mesenchymal stromal cells (MSC) [ Time Frame: Day 1- cells are counted within 24 hours of bone marrow aspirate collection ]Cell viability, proliferation profile, and expression characteristics will be evaluated.
- Characterization profile of MSC during and after expansion will be assessed [ Time Frame: Examine the cell surface marker profile of MSC using standard flow cytometry ]Cell surface expression profile will be obtained using Flow Cytometry. Additional characterization includes cell differentiation profile.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01463475
|United States, Wisconsin|
|University of Wisconsin-Madison|
|Madison, Wisconsin, United States, 53792|
|Principal Investigator:||Peiman Hematti, MD||University of Wisconsin, Madison|
|Study Director:||John M Centanni, MS||University of Wisconsin, Madison|