Resect and Discard Strategy in Clinical Practice
|ClinicalTrials.gov Identifier: NCT01462123|
Recruitment Status : Completed
First Posted : October 31, 2011
Last Update Posted : October 31, 2011
Nowadays, post-polypectomy surveillance intervals are determined by combining endoscopic and pathologic data. Real-time imaging technologies, have shown promising results in discriminating adenomatous from non-adenomatous polyps.
The "resect and discard strategy" for small polyps (based on real-time assessment of the histology and on the endoscopic resection without pathological examination) has been shown to be cost-effective in simulation models. No data exist about the impact of this strategy in clinical practice.
The aim of present study was to assess whether the systematic use, in the everyday clinical practice, of the "resect and discard strategy" allows to correctly manage patients with small colonic polyps.
|Condition or disease||Intervention/treatment|
|Endoscopic Assessment Colonic Polyps Endoscopic Surveillance NBI||Other: endoscopic assessment of colonic polyps|
|Study Type :||Observational|
|Actual Enrollment :||286 participants|
|Study Start Date :||February 2011|
small polyps patients
Patients with one small polyps at colonoscopy
|Other: endoscopic assessment of colonic polyps|
- The primary outcome of the study was to assess the agreement between "endoscopy-" and "histology-determined" surveillance strategies after small adenoma resection.
- sensitivity of the endoscopic assessment (WL coupled with NBI) of small (<10 mm) adenomas
- operative characteristics for the diagnosis of diminutive (< 5 mm) adenomas
- the feasibility of non histologic evaluation, represented by the proportion of polyps in which a in-vivo diagnosis of adenoma can be made with high confidence
- specificity of the endoscopic assessment
- accuracy of the endoscopic assessment
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01462123
|Valduce Hospital - Gastroenterology Department|
|Como, CO, Italy, 2100|