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Relationship Between Tissue Markes in Patients With Post Cardio Respiratory Syndrome

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ClinicalTrials.gov Identifier: NCT01455662
Recruitment Status : Unknown
Verified November 2011 by Vanessa Martins de oliveira, Hospital Nossa Senhora da Conceicao.
Recruitment status was:  Recruiting
First Posted : October 20, 2011
Last Update Posted : November 3, 2011
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
There is a correlation between hospital mortality and changes in markers of tissue perfusion, lactate, and venous oxygen saturation and carbon dioxide gradient.

Condition or disease
Cardiac Arrest

Detailed Description:

Evaluation of the serum carbon dioxide gradient (GapCO2), central venous saturation (ScvO2) and the clearance of serum lactate (Clac) in predicting hospital mortality after cardiac arrest syndrome (post-PCR).

Prospective study, unicenter - Intensive Care Unit - HNSC. Period: May/2010 to June/2011. Serial assessment of GapCO2 of ScvO2 Clac and the first 72 hours post-PCR. Excluded under 18, survival of less than 6HS, pregnant women, traumatized, post-operative hypothermia and liver disease. T-student test, 95% (p <0.05).


Study Design

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Relationship Between Lactate and Venous Oxygen Saturation Gradient of Carbon Dioxide in Patients With Post Cardio Respiratory Syndrome
Study Start Date : January 2010
Estimated Primary Completion Date : December 2011
Estimated Study Completion Date : December 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Cardiac Arrest
U.S. FDA Resources

Groups and Cohorts

Group/Cohort
all patients after cardiac arrest


Outcome Measures

Primary Outcome Measures :
  1. mortality [ Time Frame: 1 year ]

Secondary Outcome Measures :
  1. correlation of clearance markers of perfusion with the use of vasopressor and positive fluid balance [ Time Frame: 6 hours ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
patients hospitalized in the intensive care unit after cardiopulmonary arrest
Criteria

Inclusion Criteria:

  • All patients hospitalized in the intensive care unit after cardiopulmonary arrest with any pace

Exclusion Criteria:

pregnant women, traumatized, post-operative(less 7 days), hypothermia and liver disease.

  • patients hospitalized in the intensive care unit with more than 6 hours post cardiac arrest
  • less 18 years old
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01455662


Contacts
Contact: Vanessa M Oliveira, MD 05192513723 vanessa.oliveira480@gmail.com
Contact: Diego Riveiro, MD 05184175632 dmriveiro@yahoo.com.br

Locations
Brazil
Conceição Hospital Recruiting
Porto Alegre, Rio Grande do Sul, Brazil
Principal Investigator: Vanessa Oliveira, MD         
Principal Investigator: Diego Riveiro, MD         
Sponsors and Collaborators
Hospital Nossa Senhora da Conceicao
Investigators
Principal Investigator: Vanessa Oliveira, MD Conceição Hospital
Principal Investigator: Diego F Riveiro, MD Hospital Nossa Senhora da Conceição
More Information

Responsible Party: Vanessa Martins de oliveira, Principal Investigator, Hospital Nossa Senhora da Conceicao
ClinicalTrials.gov Identifier: NCT01455662     History of Changes
Other Study ID Numbers: 10086
First Posted: October 20, 2011    Key Record Dates
Last Update Posted: November 3, 2011
Last Verified: November 2011

Keywords provided by Vanessa Martins de oliveira, Hospital Nossa Senhora da Conceicao:
cardiac arrest

Additional relevant MeSH terms:
Heart Arrest
Heart Diseases
Cardiovascular Diseases