The Relationship Between Allergic Rhinitis and Geographic Tongue (AR-GT)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified October 2011 by China Medical University Hospital.
Recruitment status was  Recruiting
Information provided by (Responsible Party):
China Medical University Hospital Identifier:
First received: October 4, 2011
Last updated: October 18, 2011
Last verified: October 2011

Allergic rhinitis is a complex chronic inflammatory disease, it always presents with nasal obstruction, nasal itching, sneezing and runny nose. Whether in adults or children, rhinitis is a complex disease. The prevalence of allergic rhinitis in Taiwan is about 24-29%. Taiwan is a developing country. It is a hot and humid country. In developing countries, industrialization, air pollution makes the constantly increasing number of patients with rhinitis. Penghu in 1994 for children aged 7 to 14 by the study found that among 7599 people, 1766 people have allergic rhinitis, about 23.2%. Allergic rhinitis is a complex chronic disease. So, it become a diagnostic challenge, its prevalence always underestimated. The prevalence of rhinitis has increased in recent years. The phenomenon of underestimate is caused by variety of personal and environmental factors. Allergic rhinitis had increased direct and indirect social and economic burden.

Geographic tongue is a benign tongue performance. Geographic tongue has been reported their relevance to allergy. Geographic tongue is a chronic tongue situation. The causes of geographic tongue still remains unknown. Allergic rhinitis is a diagnostic challenge to clinicians. The investigators hope that geographic tongue could play a role in the diagnostic of allergic rhinitis. The prevalence of geographic tongue in the United States is about 1.8%, white Americans and Mexicans have a higher incidence rate. This study will investigate the relevance between allergic rhinitis and geographic tongue. The investigators will analyze the relevant gender, age, severity of inspection reports. The research results wound provide an important reference to the diagnosis of allergic rhinitis.

Allergic Rhinitis
Geographic Tongue

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by China Medical University Hospital:

Primary Outcome Measures:
  • Number of participants with Adverse Events [ Time Frame: 8th month ] [ Designated as safety issue: Yes ]

Estimated Enrollment: 300
Study Start Date: September 2011
Estimated Study Completion Date: September 2012
Estimated Primary Completion Date: March 2012 (Final data collection date for primary outcome measure)
Allergy rhinitis
Allergy rhinitis patients group
Non- Allergy rhinitis
Non- Allergy rhinitis patients group


Ages Eligible for Study:   20 Years to 89 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Group 1: Allergy rhinitis Group 2: Non-allergy rhinitis

Inclusion Criteria:

  • rhinitis and non-rhinitis patients
  • willing to complete the study
  • no limitation of tongue movement

Exclusion Criteria:

  • more than 90 years old or younger than 20 years old
  • unable to complete the study
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01454492

China Medical University Hospital Recruiting
Taichung, Taiwan, 404
Contact: Chih-Jaan Tai, M.D.   
Principal Investigator: Chih-Jaan Tai, M.D.         
Sponsors and Collaborators
China Medical University Hospital
Principal Investigator: CJ Tai, M.D. China Medical University Hospital
  More Information

Responsible Party: China Medical University Hospital Identifier: NCT01454492     History of Changes
Other Study ID Numbers: CMUH-3485 
Study First Received: October 4, 2011
Last Updated: October 18, 2011
Health Authority: Taiwan: Institutional Review Board

Keywords provided by China Medical University Hospital:
Allergy rhinitis
Geographic tongue

Additional relevant MeSH terms:
Glossitis, Benign Migratory
Rhinitis, Allergic
Hypersensitivity, Immediate
Immune System Diseases
Mouth Diseases
Nose Diseases
Otorhinolaryngologic Diseases
Respiratory Hypersensitivity
Respiratory Tract Diseases
Respiratory Tract Infections
Stomatognathic Diseases
Tongue Diseases processed this record on May 26, 2016