Genetics, Brain Structure and Thinking Skills in Autism
|ClinicalTrials.gov Identifier: NCT01451983|
Recruitment Status : Completed
First Posted : October 14, 2011
Results First Posted : January 14, 2015
Last Update Posted : January 14, 2015
|Condition or disease|
|Autism Spectrum Disorders|
|Study Type :||Observational|
|Actual Enrollment :||138 participants|
|Observational Model:||Case Control|
|Official Title:||Genetic, Biochemical, Behavioral and Neuroimaging Phenotypes of Autism Spectrum Disorders (ASDs)|
|Study Start Date :||May 2010|
|Primary Completion Date :||August 2014|
|Study Completion Date :||August 2014|
ASD with PTEN
Individuals with autism spectrum disorder who are also found to have a PTEN mutation.
ASD no PTEN macrocephaly
Individuals with autism spectrum disorder who do not have a PTEN mutation with a large head circumference.
ASD no PTEN no macrocephaly
Individuals with autism spectrum disorder who do not have a PTEN mutation without a large head circumference.
Siblings of individuals with autism spectrum disorders.
- Total Brain Volume [ Time Frame: Baseline ]
Biospecimen Retention: Samples With DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01451983
|United States, Ohio|
|Cleveland Clinic Center for Autism|
|Cleveland, Ohio, United States, 44104|
|Principal Investigator:||Thomas W Frazier, Ph.D.||The Cleveland Clinic|
|Principal Investigator:||Charis Eng, M.D., Ph.D.||The Cleveland Clinic|