Genetics, Brain Structure and Thinking Skills in Autism
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01451983|
Recruitment Status : Completed
First Posted : October 14, 2011
Results First Posted : January 14, 2015
Last Update Posted : January 14, 2015
|Condition or disease|
|Autism Spectrum Disorders|
|Study Type :||Observational|
|Actual Enrollment :||138 participants|
|Observational Model:||Case Control|
|Official Title:||Genetic, Biochemical, Behavioral and Neuroimaging Phenotypes of Autism Spectrum Disorders (ASDs)|
|Study Start Date :||May 2010|
|Actual Primary Completion Date :||August 2014|
|Actual Study Completion Date :||August 2014|
ASD with PTEN
Individuals with autism spectrum disorder who are also found to have a PTEN mutation.
ASD no PTEN macrocephaly
Individuals with autism spectrum disorder who do not have a PTEN mutation with a large head circumference.
ASD no PTEN no macrocephaly
Individuals with autism spectrum disorder who do not have a PTEN mutation without a large head circumference.
Siblings of individuals with autism spectrum disorders.
- Total Brain Volume [ Time Frame: Baseline ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01451983
|United States, Ohio|
|Cleveland Clinic Center for Autism|
|Cleveland, Ohio, United States, 44104|
|Principal Investigator:||Thomas W Frazier, Ph.D.||The Cleveland Clinic|
|Principal Investigator:||Charis Eng, M.D., Ph.D.||The Cleveland Clinic|