Cognitive Remediation for Neuropsychological Impairment in Compulsive Hoarding
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01451697|
Recruitment Status : Unknown
Verified October 2011 by Hartford Hospital.
Recruitment status was: Recruiting
First Posted : October 14, 2011
Last Update Posted : October 14, 2011
|Condition or disease||Intervention/treatment||Phase|
|Hoarding Disorder Attentional Impairment||Behavioral: Cognitive Remediation Behavioral: Control (Placebo)||Early Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||20 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Cognitive Remediation for Neuropsychological Impairment in Compulsive Hoarding|
|Study Start Date :||July 2011|
|Estimated Primary Completion Date :||July 2012|
|Estimated Study Completion Date :||October 2012|
Experimental: Experimental: Cognitive Remediation
The remediation intervention will consist of a sequence of computerized cognitive exercises designed to improve a variety of aspects of attention, through repeated drill-and-practice (Bell, Bryson, Greig, Corcoran, & Wexler, 2001; Bracy, 1995; Kurtz et al., 2007). Exercises will be started and continued at the highest level of difficulty, in order to best establish improvement over time. Components of the planned intervention produce performance gains on practiced tasks (e.g., Wexler et al., 1997) and generalization of improvement to other tasks (Kurtz et al., 2007). All training on computer exercises will be conducted with coaching from staff trained in these procedures.
Behavioral: Cognitive Remediation
A computerized cognitive remediation program focused on attentional training will be used.
Placebo Comparator: Control (Placebo)
The placebo control condition will consist of structured relaxation training, which will involve viewing and participating with meditation and stress-reduction DVDs, and listening to and following a CD of Progressive Muscle Relaxation. Participants will benefit from learning stress reduction techniques in this condition, but will not exercise any of the cognitive domains of interest targeted in the treatment group.
Behavioral: Control (Placebo)
The control condition will involve relaxation training.
- Continuous Performance Task (computerized version): change from Baseline in Attentional Functioning at 8 Weeks [ Time Frame: Week 0 (Baseline) and Week 8 (Endpoint) ]This measure is a computerized assessment of attention, memory, and executive functioning. The investigators will use this measure to assess change in those cognitive domains between Baseline (Week 0) and Endpoint (Week 8).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01451697
|Contact: Jennifer DiMauro, BAfirstname.lastname@example.org|
|Contact: David F Tolin, PhDemail@example.com|
|United States, Connecticut|
|Anxiety Disorders Center, Institute of Living/Hartford||Recruiting|
|Hartford, Connecticut, United States, 06106|
|Contact: Jennifer DiMauro, BA 860-545-7707 firstname.lastname@example.org|
|Contact: David F Tolin, PhD 860-545-7685 email@example.com|
|Principal Investigator: Jennifer DiMauro, BA|
|Sub-Investigator: David F Tolin, PhD|
|Sub-Investigator: Johanna Kaplan, PhD|
|Principal Investigator:||Jennifer DiMauro, BA||Hartford Hospital|
|Study Director:||David F Tolin, PhD||Hartford Hospital|