Effect of Essential Oils in Aromatherapy on Emotional Relaxation

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Surasak Saokaew, University of Phayao
ClinicalTrials.gov Identifier:
NCT01443871
First received: September 28, 2011
Last updated: May 26, 2015
Last verified: May 2015
  Purpose

The purpose of this study is to examine and compare electroencephalography (EEG) changes in human subjects directly after inhalation of essential oils from five Thai aromatherapies. The investigators hypothesize that essential oils from Thai aromatherapies may influence the human EEG involving emotional relaxation particularly alpha wave EEG.


Condition Intervention
Healthy
Other: Aromatherapy
Other: Pure water

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Official Title: Effect of Essential Oils in Aromatherapy on Emotional Relaxation

Resource links provided by NLM:


Further study details as provided by University of Phayao:

Primary Outcome Measures:
  • electroencephalography (EEG) changes [ Time Frame: baseline, 10 minutes ] [ Designated as safety issue: No ]
    The EEG was assessed for 10 minutes in each period; baseline, during and after inhaled the essential oil


Enrollment: 48
Study Start Date: September 2011
Study Completion Date: December 2014
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Aromatherapy
Experimental procedures were conducted in the morning. Subjects individually entered the closed room where the temperature was kept at 25-26 oC and humidity 50-60%. The subjects were blinded using mask and were seated comfortably with eyes closed during experimental period. The EEG was recorded using silver electrodes. EEG activity was monitored 4 areas (F7, F8, T3 and T4) and ground electrodes. The experiments were divided into 3 parts. The first part, no-odor were recorded EEG activity for 10 minutes as a baseline. The second part, subject was exposure to the odor for 10 minutes as during inhalation. The last part, the odor was dispersed and assessed EEG activity for 10 minutes as after inhalation.
Other: Aromatherapy
Subject will assigned inhale aromatherapy
Placebo Comparator: Pure water
Experimental procedures were conducted in the morning. Subjects individually entered the closed room where the temperature was kept at 25-26 oC and humidity 50-60%. The subjects were blinded using mask and were seated comfortably with eyes closed during experimental period. The EEG was recorded using silver electrodes. EEG activity was monitored 4 areas (F7, F8, T3 and T4) and ground electrodes. The experiments were divided into 3 parts. The first part, no-odor were recorded EEG activity for 10 minutes as a baseline. The second part, subject was exposure to the water for 10 minutes as during inhalation. The last part, the water was dispersed and assessed EEG activity for 10 minutes as after inhalation.
Other: Pure water
Subject will assigned inhale Pure water

Detailed Description:

The subjects consisted of 22 male and 26 female subjects , ages between 20 to 30 years (mean age, 23.3 years). They were screened for excessive nasal congestion, drug and food taken, and neurological disorders prior to participation in the experiment. The experiments were approved by the Ethical Committee for Research Involving Human Research Subject, Naresuan University. All subjects read and signed an informed consent before participation.

  Eligibility

Ages Eligible for Study:   18 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • > 18 years old

Exclusion Criteria:

  • excessive nasal congestion
  • neurological disorders prior to participation in the experiment
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01443871

Locations
Thailand
Surasak Saokaew
Muang, Phayao, Thailand, 56000
University of Phayao
Muang, Phayao, Thailand, 56000
Sponsors and Collaborators
University of Phayao
Investigators
Principal Investigator: Surasak Saokaew, PhD University of Phayao
  More Information

No publications provided

Responsible Party: Surasak Saokaew, Co-Principal Investigator, University of Phayao
ClinicalTrials.gov Identifier: NCT01443871     History of Changes
Other Study ID Numbers: WP-5102031
Study First Received: September 28, 2011
Last Updated: May 26, 2015
Health Authority: Thailand: Institutional Review Board

Keywords provided by University of Phayao:
Volunteer

ClinicalTrials.gov processed this record on July 30, 2015