Study of Echocardiogram Accuracy in Patients With Mitral Valve Calcification
|ClinicalTrials.gov Identifier: NCT01442467|
Recruitment Status : Terminated (Subject accrual too difficult)
First Posted : September 28, 2011
Last Update Posted : April 1, 2013
This study aims to evaluate the accuracy of the echocardiographic data obtained from patients with calcifications in the mitral valve who are undergoing a cardiac (heart) catheterization.
Echocardiography is a non-invasive (does not break the skin) procedure used to see an image of the heart. It uses harmless sound waves to create an image of the heart on a computer screen. These images will show the valves of the heart, how well the heart is pumping blood, the blood flow across these valves and how large the heart is. A silver paddle-shaped device is moved easily over the skin to capture these images.
Calcification (hardening) of the heart valves and heart rings (fibrous tissue surrounding the valves) is a common finding and it increases with age. The presence of calcification changes the blood flow through the heart valves. This makes any echocardiographic data (information) obtained from patients with calcifications difficult to interpret.
|Condition or disease|
|Mitral Annulus Calcification|
|Study Type :||Observational|
|Actual Enrollment :||4 participants|
|Observational Model:||Case Control|
|Official Title:||Correlation Between Echocardiographic Indices of Diastolic Function (E/E`) and Left Ventricular End Diastolic Pressure (LVEDP) in Patients With Mitral Annular Calcification|
|Study Start Date :||June 2011|
|Actual Primary Completion Date :||January 2013|
|Actual Study Completion Date :||January 2013|
|Mild to Severe MAC|
|No to mild MAC|
- Agreement between invasive and non-invasive measures of LVEDP [ Time Frame: participants will be followed for the duration of hospital stay, an expected average of 2 days ]evaluate the agreement between the E/E` ratio by echocardiography and the left ventricular end-diastolic pressure by cardiac catheterization in patients with moderate to severe mitral annular calcification
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01442467
|United States, Nebraska|
|Creighton Unviversity Medical Center|
|Omaha, Nebraska, United States, 68131|