Sevoflurane, Propofol, Postoperative Pain
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ClinicalTrials.gov Identifier: NCT01437462 |
Recruitment Status
:
Completed
First Posted
: September 21, 2011
Last Update Posted
: April 10, 2013
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Healthy Adults Gynecological Disease | Drug: Sevoflurane Drug: Propofol | Phase 4 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 168 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Single (Participant) |
Primary Purpose: | Treatment |
Official Title: | Postoperative Pain After Propofol Sevoflurane Anaesthesia: a Prospective, Randomized, Single-blinded Trial |
Study Start Date : | October 2008 |
Actual Primary Completion Date : | March 2013 |
Actual Study Completion Date : | March 2013 |

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Drug: Sevoflurane
- Postoperative consumption of an opioid (oxycodone) [ Time Frame: 20 hours ]The consumption of oxycodone will be monitored by recording the amount of the drug received via a commercially available patient controlled analgesia (PCA) pump.
- NRS (numeral rating scale) of pain [ Time Frame: 20 hours ]NRS is evaluated frequently during the study period.

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Ages Eligible for Study: | 18 Years to 69 Years (Adult, Senior) |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Age 18-69 years
- Gender: female
- ASA status 1-3
- Laparoscopic hysterectomy
Exclusion Criteria:
- Body Mass Index over 35
- Diabetes mellitus
- Liver disease
- Allergies to pharmaceuticals used in the Study
- Present use of opioids

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01437462
Finland | |
Tampere University Hospital | |
Tampere, Finland, 33521 |
Responsible Party: | Arvi Yli-Hankala, Professor, Tampere University Hospital |
ClinicalTrials.gov Identifier: | NCT01437462 History of Changes |
Other Study ID Numbers: |
Satu_Pokkinen_01_2011 |
First Posted: | September 21, 2011 Key Record Dates |
Last Update Posted: | April 10, 2013 |
Last Verified: | April 2013 |
Keywords provided by Arvi Yli-Hankala, Tampere University Hospital:
Pain, Postoperative Anesthetics, intravenous Anesthetics, inhalation Otherwise healthy adults undergoing general anesthesia for gynecological disease. |
Additional relevant MeSH terms:
Pain, Postoperative Genital Diseases, Female Pain Neurologic Manifestations Nervous System Diseases Postoperative Complications Pathologic Processes Signs and Symptoms Anesthetics |
Propofol Sevoflurane Central Nervous System Depressants Physiological Effects of Drugs Hypnotics and Sedatives Anesthetics, Intravenous Anesthetics, General Platelet Aggregation Inhibitors Anesthetics, Inhalation |