This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Molecular Mediators of Nerve Injury Signaling

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified September 2011 by Rambam Health Care Campus.
Recruitment status was:  Enrolling by invitation
Information provided by (Responsible Party):
Rambam Health Care Campus Identifier:
First received: September 19, 2011
Last updated: NA
Last verified: September 2011
History: No changes posted
Specific proteins and other signaling molecules are increased and decreased following nerve injury. Some of these are important in producing pain or explaining why pain persists after traumatic nerve injuries or in disease states such as diabetes. In this study, the investigators hypothesize that it is possible to detect changes in specific signaling molecules and that these will provide insights into novel treatment strategies. The patients to be included are those who are undergoing the removal of tissue during surgery. The tissues that would otherwise be discarded will be included in the study as appropriate.

Diabetes Nerve Injury Chronic Neuropathic Pain

Study Type: Observational
Study Design: Observational Model: Ecologic or Community
Time Perspective: Prospective
Official Title: Molecular Mediators of Nerve Injury Signaling

Further study details as provided by Rambam Health Care Campus:

Estimated Enrollment: 50
Study Start Date: September 2011
Estimated Primary Completion Date: September 2016 (Final data collection date for primary outcome measure)
Nerve injury


Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients undergoing surgical procedures at Rambam Health Care Campus wherein the surgeon and PI determine appropriateness for study

Inclusion Criteria:

  • patients undergoing surgery where tissue removal is anticipated

Exclusion Criteria:

  • age younger than 18
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01437332

Rambam Health Care Campus
Haifa, Israel, 31096
Sponsors and Collaborators
Rambam Health Care Campus
  More Information

Responsible Party: Rambam Health Care Campus Identifier: NCT01437332     History of Changes
Other Study ID Numbers: 0356-11-RMB
Study First Received: September 19, 2011
Last Updated: September 19, 2011

Additional relevant MeSH terms:
Wounds and Injuries
Neurologic Manifestations
Nervous System Diseases
Peripheral Nervous System Diseases
Neuromuscular Diseases
Signs and Symptoms processed this record on August 17, 2017