Molecular Mediators of Nerve Injury Signaling

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01437332
Recruitment Status : Unknown
Verified September 2011 by Rambam Health Care Campus.
Recruitment status was:  Enrolling by invitation
First Posted : September 20, 2011
Last Update Posted : September 20, 2011
Information provided by (Responsible Party):
Rambam Health Care Campus

Brief Summary:
Specific proteins and other signaling molecules are increased and decreased following nerve injury. Some of these are important in producing pain or explaining why pain persists after traumatic nerve injuries or in disease states such as diabetes. In this study, the investigators hypothesize that it is possible to detect changes in specific signaling molecules and that these will provide insights into novel treatment strategies. The patients to be included are those who are undergoing the removal of tissue during surgery. The tissues that would otherwise be discarded will be included in the study as appropriate.

Condition or disease
Diabetes Nerve Injury Chronic Neuropathic Pain

Study Type : Observational
Estimated Enrollment : 50 participants
Observational Model: Ecologic or Community
Time Perspective: Prospective
Official Title: Molecular Mediators of Nerve Injury Signaling
Study Start Date : September 2011
Estimated Primary Completion Date : September 2016

Nerve injury

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients undergoing surgical procedures at Rambam Health Care Campus wherein the surgeon and PI determine appropriateness for study

Inclusion Criteria:

  • patients undergoing surgery where tissue removal is anticipated

Exclusion Criteria:

  • age younger than 18

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01437332

Rambam Health Care Campus
Haifa, Israel, 31096
Sponsors and Collaborators
Rambam Health Care Campus

Responsible Party: Rambam Health Care Campus Identifier: NCT01437332     History of Changes
Other Study ID Numbers: 0356-11-RMB
First Posted: September 20, 2011    Key Record Dates
Last Update Posted: September 20, 2011
Last Verified: September 2011

Additional relevant MeSH terms:
Wounds and Injuries
Neurologic Manifestations
Nervous System Diseases
Peripheral Nervous System Diseases
Neuromuscular Diseases
Signs and Symptoms