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Genetic Contribution of Pain and Inflammation in IBS

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ClinicalTrials.gov Identifier: NCT01436760
Recruitment Status : Completed
First Posted : September 20, 2011
Last Update Posted : March 26, 2012
Sponsor:
Information provided by (Responsible Party):
University of Florida

Study Description
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information
Brief Summary:
The goal of the study is to identify possible polymorphisms on the loci of candidate genes that may be involved in modulation of pain and inflammation in irritable bowel syndrome.

Condition or disease
Irritable Bowel Syndrome

Detailed Description:
Stored and de-linked blood or DNA from subjects with IBS will be utilized for analysis for possible polymorphisms at predetermined genetic loci located in chosen genes.

Study Design
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Study Type : Observational
Actual Enrollment : 72 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Genetic Contribution of Pain and Inflammation in Irritable Bowel Syndrome.
Study Start Date : May 2011
Actual Primary Completion Date : March 2012
Actual Study Completion Date : March 2012
Groups and Cohorts
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information


Outcome Measures
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Primary Outcome Measures :
  1. Polymorphisms [ Time Frame: one year ]
    The goal of the study isd to identify possible polymorphisms on the loci of canidate genes that may be involved in modulation of pain and inflammation in irritable Bowel Syndrome.


Biospecimen Retention:   Samples With DNA
The delinked blood/DNA is stored in the genetics laboratory and they will be analyzed for possible polymorphisms

Eligibility Criteria
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Generic laboratory blood bank
Criteria

Inclusion Criteria:

  • Subjects with IBS and previously stored samples

Exclusion Criteria:

  • Subjects without IBS and no previously stored samples
Contacts and Locations
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01436760


Locations
United States, Florida
University of Florida
Gainesville, Florida, United States, 32610
Sponsors and Collaborators
University of Florida
Investigators
Principal Investigator: Baharak Moshiree, MD, MS University of Florida
More Information
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Responsible Party: University of Florida
ClinicalTrials.gov Identifier: NCT01436760     History of Changes
Other Study ID Numbers: 132-2011
First Posted: September 20, 2011    Key Record Dates
Last Update Posted: March 26, 2012
Last Verified: March 2012

Keywords provided by University of Florida:
IBS

Additional relevant MeSH terms:
Syndrome
Inflammation
Irritable Bowel Syndrome
Disease
Pathologic Processes
 Colonic Diseases, Functional
Colonic Diseases
Intestinal Diseases
Gastrointestinal Diseases
Digestive System Diseases