Genetic Contribution of Pain and Inflammation in IBS

This study has been completed.

Sponsor:

Information provided by (Responsible Party):

University of Florida

ClinicalTrials.gov Identifier:

NCT01436760

First received: September 16, 2011

Last updated: March 23, 2012

Last verified: March 2012

History of Changes

Purpose

The goal of the study is to identify possible polymorphisms on the loci of candidate genes that may be involved in modulation of pain and inflammation in irritable bowel syndrome.

Condition
Irritable Bowel Syndrome


Study Type:	Observational
Study Design:	Observational Model: Case-Only Time Perspective: Retrospective
Official Title:	Genetic Contribution of Pain and Inflammation in Irritable Bowel Syndrome.

Further study details as provided by University of Florida:

Primary Outcome Measures:

Polymorphisms [ Time Frame: one year ] [ Designated as safety issue: No ]
The goal of the study isd to identify possible polymorphisms on the loci of canidate genes that may be involved in modulation of pain and inflammation in irritable Bowel Syndrome.

Biospecimen Retention: Samples With DNA

The delinked blood/DNA is stored in the genetics laboratory and they will be analyzed for possible polymorphisms


Enrollment:	72
Study Start Date:	May 2011
Study Completion Date:	March 2012
Primary Completion Date:	March 2012 (Final data collection date for primary outcome measure)

Detailed Description:

Stored and de-linked blood or DNA from subjects with IBS will be utilized for analysis for possible polymorphisms at predetermined genetic loci located in chosen genes.

Eligibility


Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Probability Sample

Study Population

Generic laboratory blood bank

Criteria

Inclusion Criteria:

Subjects with IBS and previously stored samples

Exclusion Criteria:

Subjects without IBS and no previously stored samples

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01436760

Locations


United States, Florida
University of Florida
Gainesville, Florida, United States, 32610

Sponsors and Collaborators

University of Florida

Investigators


Principal Investigator:	Baharak Moshiree, MD, MS	University of Florida

More Information

No publications provided


Responsible Party:	University of Florida
ClinicalTrials.gov Identifier:	NCT01436760 History of Changes
Other Study ID Numbers:	132-2011
Study First Received:	September 16, 2011
Last Updated:	March 23, 2012
Health Authority:	United States: Institutional Review Board

Keywords provided by University of Florida:


IBS

Additional relevant MeSH terms:


Inflammation Irritable Bowel Syndrome Syndrome Colonic Diseases Colonic Diseases, Functional	Digestive System Diseases Disease Gastrointestinal Diseases Intestinal Diseases Pathologic Processes

ClinicalTrials.gov processed this record on February 26, 2015

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