Detection of Helicobacter Pylori Infection by High Resolution Endoscopy
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Although endoscopic findings of H. pylori have been reported in the literature, there is still some debate over whether H. pylori-related gastritis can be diagnosed via endoscopic features alone. Most studies concluded that it is not possible to diagnose H. pylori-related gastritis on the basis of endoscopic findings. However, the resolution power of endoscopy has greatly improved in recent years and the exact examination of gastric mucosa was possible.
Condition or disease
Our study aimed to achieve the following: (1) describe the H. pylori-related mucosal pattern in the gastric corpus using high-definition endoscopy; (2) evaluate the diagnostic accuracy for H. pylori detection; (3) find the optimal biopsy site for rapid urease test (RUT); (4) validate the inter- and intraobserver agreement in the assessment of endoscopic patterns.
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Ages Eligible for Study:
20 Years to 70 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients who underwent upper endoscopy in the Kyung Hee University Hospital
Patients who underwent upper endoscopy
Age < 20 or > 70
Severe systemic disease or advanced chronic liver disease
Medication history of NSAID, PPI, H2 blockers or antibiotics
History of H. pylori eradication therapy
History of gastric surgery
Recent history of upper GI bleeding
Gastric or duodenal ulcer (including old scar change) during endoscopy