Value of PET/CT Imaging in the Diagnosis of Permanent Central Venous Catheters Infection
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ClinicalTrials.gov Identifier: NCT01434797 |
Recruitment Status
:
Recruiting
First Posted
: September 15, 2011
Last Update Posted
: November 15, 2016
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Condition or disease |
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Infection |
Study Type : | Observational |
Estimated Enrollment : | 40 participants |
Observational Model: | Case Control |
Time Perspective: | Prospective |
Official Title: | Prospective Study on the Usefulness and Diagnostic Value of F-18-FDG PET/CT in the Diagnosis of Permanent Central Venous Catheters Infection |
Study Start Date : | September 2011 |
Estimated Primary Completion Date : | December 2017 |
Estimated Study Completion Date : | January 2018 |
Group/Cohort |
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Confirmed CVCP infection before removal
Patients with permanent central venous catheter infection confirmed by conventional method
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Presumed CPVP infection before removal
Patients with probable permanent central venous catheter infection (standard methods for infection detection not conclusive)
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Uninfected CVCP before removal
Patients with planned permanent central venous catheter removal (no infection)
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- Diagnostic value (sensitivity and sensibility, positive/negative predictive value) of F-18-FDG PET/CT imaging in the detection of CVCP infection [ Time Frame: 6 months ]To determine the clinical use of PET/CT in the detection of catheter infection by comparing PET/CT imaging results to standard means of catheter infection detection (i.e. clinical signs and hemoculture [positive or negative])
- Diagnostic value (sensitivity and sensibility, positive/negative predictive value) of microcalorimetry in the detection of CVCP infection [ Time Frame: 6 months ]To determine the clinical use of microcalorimetry in the detection of catheter infection by comparing microcalorimetry results to standard means of catheter infection detection (i.e. clinical signs and hemoculture [positive or negative])

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Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- patients with confirmed catheter infection requiring surgical removal
- patients with probable catheter infection requiring surgical removal
- patients with planned removal of uninfected catheter
- ≥18years old
Exclusion Criteria:
- extreme claustrophobia
- pregnancy and breastfeeding
- severe septicemia

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01434797
Contact: John O Prior, PhD MD | +41 21 314 43 48 | john.prior@chuv.ch |
Switzerland | |
Centre Hospitalier Universitaire Vaudois, Nuclear Medicine | Recruiting |
Lausanne, Vaud, Switzerland, 1011 | |
Sub-Investigator: François Saucy, MD | |
Sub-Investigator: Andrej Trampuz, MD |
Principal Investigator: | John O Prior, PhD MD | Centre Hospitalier Universitaire Vaudois and University of Lausanne |
Responsible Party: | John O. Prior, Centre Hospitalier Universitaire Vaudois, Nuclear Medicine, University of Lausanne Hospitals |
ClinicalTrials.gov Identifier: | NCT01434797 History of Changes |
Other Study ID Numbers: |
89/11 |
First Posted: | September 15, 2011 Key Record Dates |
Last Update Posted: | November 15, 2016 |
Last Verified: | November 2016 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | No |
Keywords provided by John O. Prior, University of Lausanne Hospitals:
Infection Permanent central venous catheter Device Related |
Additional relevant MeSH terms:
Infection Communicable Diseases |