The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
Evaluate brain tissue oxygenation assessing the number and percentage of subjects from whom regional data could be collected during 90% of the aortic arch surgery, and the registration rate during deep hypothermic circulatory arrest. [ Time Frame: At the end of the surgical case approximately 6 to 8 hours ]
Secondary Outcome Measures
Determine whether there are unilateral or global differences in cerebral tissue oxygenation detected during selective antegrade cerebral perfusion [ Time Frame: At the end of the surgical case approximately 6 to 8 hours ]
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Mayo Clinic and affiliated hospitals
Is male or female
Is of any race or ethnicity
Is greater than or equal to eighteen (18) years of age
Weighs greater than or equal to 40 kilogram
Is not known to be pregnant
Is undergoing aortic arch surgery with planned deep hypothermia circulatory arrest, either with or without select antegrade cerebral perfusion
Is able and willing to provide informed consent
Is less than eighteen (18) years of age
Weighs less than 40 kilogram
Is known to be pregnant
Does not understand English
Has known sensitivity to adhesives
Is unable or unwilling to provide informed consent