Study of Prevalence of Colorectal Adenoma in 30- to 49-year-old Subjects With a Family History of Colorectal Cancer
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT01428752 |
Recruitment Status : Unknown
Verified September 2011 by Jaeil Kim, Asan Medical Center.
Recruitment status was: Recruiting
First Posted : September 5, 2011
Last Update Posted : September 9, 2011
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Current guidelines for initiating screening colonoscopies in patients younger than 50 years of age who have a first relative history of colorectal cancer are controversial. The aim of this study was to prospectively define the prevalence of colorectal adenoma 30- to 49-years-old asymptomatic subjects with a first relative history of colorectal cancer and to compare the data with controls.
Design: Single-center prospective study
Condition or disease |
---|
Colorectal Neoplasms |
Study Type : | Observational |
Estimated Enrollment : | 1000 participants |
Observational Model: | Cohort |
Time Perspective: | Prospective |
Official Title: | Prevalence of Colorectal Adenoma in 30- to 49-year-old Asymptomatic Subjects With a First Relative History of Colorectal Cancer |
Study Start Date : | September 2011 |
Estimated Primary Completion Date : | September 2014 |
Estimated Study Completion Date : | September 2014 |

Group/Cohort |
---|
Family history
30- to 49-year-old asymptomatic subjects with a first relative history of colorectal cancer
|
- prevalence of colorectal adenoma(any size) [ Time Frame: First screening colonoscopy ]
- prevalence of advanced adenoma [ Time Frame: First screening colonoscopy ]
- Any adenoma ≥10 mm
- Any villous component
- High-grade dysplasia
Biospecimen Retention: Samples Without DNA

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 30 Years to 49 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- 30- to 49-year-old asymptomatic subjects
- First relative history of colorectal cancer
Exclusion Criteria:
- previous colonoscopy for any reason
- personal history of colorectal adenomas or CRC
- history of familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, or inflammatory bowel disease
- documented history of occult GI bleeding, lower gastrointestinal tract bleeding not attributable to hemorrhoid, or
- iron deficiency anemia
- unexplained weight loss of >10% of the body weight in the 6 months before colonoscopy
- incomplete examination of entire colon

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01428752
Contact: JAEIL KIM, M.D | 82230105673 | pianojaeil@nate.com | |
Contact: KYUNG-JO KIM, M.D | 82230103196 | capsulendos@gmail.com |
Korea, Republic of | |
Asan Medical Center | Recruiting |
Seoul, Korea, Republic of, 138-736 | |
Contact: Kyung-Jo Kim, M.D 82230103196 capsulendos@gmail.com | |
Contact: Jaeil Kim, M.D 82230105673 pianojaeil@nate.com |
Study Director: | Kyung-Jo Kim, M.D | Department of Gastroenterology, Asan Medical Center |
Responsible Party: | Jaeil Kim, Clinical Assistant Professor, Asan Medical Center |
ClinicalTrials.gov Identifier: | NCT01428752 |
Other Study ID Numbers: |
ADENOMA 30-49 YO |
First Posted: | September 5, 2011 Key Record Dates |
Last Update Posted: | September 9, 2011 |
Last Verified: | September 2011 |
colonoscopy colorectal neoplasms screening family history |
Colorectal Neoplasms Adenoma Neoplasms Intestinal Neoplasms Gastrointestinal Neoplasms Digestive System Neoplasms Neoplasms by Site |
Digestive System Diseases Gastrointestinal Diseases Colonic Diseases Intestinal Diseases Rectal Diseases Neoplasms, Glandular and Epithelial Neoplasms by Histologic Type |