Matching Cognitive Remediation to Cognitive Deficits in Substance-Abusing Inmates
This is a 2 -year NIDA funded grant (Co-PIs: Joseph P. Newman, John Curtin, and Carl Lejuez) that examines whether recent progress in characterizing the cognitive deficits associated with psychopathic and externalizing offenders may be used to develop better therapeutic interventions to treat their substance abuse and other self-control problems. Inmates with externalizing or psychopathy will receive one of two computer-based interventions to remediate the core cognitive skills that have been linked to self-regulation deficits in the two groups. One intervention (ACC) targets the affective cognitive control deficits associated with externalizing offenders whereas the other intervention (ATC) targets the attention to context deficits associated with psychopathic offenders. The specific components of the project include: selection and randomization of inmates; pre- and post-treatment behavioral and brain-related (ERP and Startle) measures to evaluate the impact and specificity of the ACC and ATC treatments; and 6 sessions of behavioral (e.g. computerized) and verbal training in ACC or ATC.
|Study Design:||Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Treatment
|Official Title:||Matching Cognitive Remediation to Cognitive Deficits in Substance-Abusing Inmates|
- Psychophysiological change from pre-treatment to post-treatment [ Time Frame: 6 weeks after pre-testing ] [ Designated as safety issue: No ]We will measure electrophysiology (EEG), startle responses (EMG measured in microvolts), and behavioral responses on six tasks that measure such processes as affective regulation, distress tolerance, cognitive control, selective attention, and attending to context.
- Frequency of Conduct Reports [ Time Frame: within 3 months of participation ] [ Designated as safety issue: No ]Assess change in the frequency of institution conduct reports post-treatment. We will compare frequency of these reports pre-treatment and post-treatment.
|Study Start Date:||May 2011|
|Study Completion Date:||May 2013|
|Primary Completion Date:||May 2013 (Final data collection date for primary outcome measure)|
|Experimental: Attention to Context||
Other: Cognitive Remediation
Computer training on 3 tasks that targets the attention to context deficits associated with psychopathic offenders. Participants complete 6 training sessions, that include the tasks, feedback and real-world translational examples.
|Experimental: Affective Cognitive Control||
Other: Cognitive Remediation
Computer training on 3 tasks that targets the affective cognitive control deficits associated with externalizing offenders. Participants complete 6 training sessions, that include the tasks, feedback and real-world translational examples.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01428349
|United States, Wisconsin|
|Fox Lake Correctional Institution|
|Fox Lake, Wisconsin, United States, 53933|
|Oshkosh Correctional Institution|
|Oshkosh, Wisconsin, United States, 54901|
|Principal Investigator:||Joseph P Newman, Ph.D.||University of Wisconsin, Madison|