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Monovision for the Treatment of Diplopia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01426672
Recruitment Status : Completed
First Posted : August 31, 2011
Last Update Posted : August 31, 2011
Information provided by:
Mount Sinai Hospital, Canada

Brief Summary:


The purpose of this study is to quantitatively assess the efficacy of monovision correction in the treatment of acquired small angle binocular diplopia in adult patients.


Twenty patients with symptomatic diplopia were enrolled in a prospective treatment trial. All had stable deviations of 10 prism diopters or less for over three months. Each received monovision spectacles and/ or contact lenses with distance correction in the dominant eye. Half received a +3.00 diopter (D) add and the others received +2.50 D. The validated and standardized Diplopia Questionnaire and Amblyopia and Strabismus Questionnaire (ASQE) were used to quantify the efficacy of monovision correction for diplopia by measuring the functional impact on vision-specific quality of life.

Condition or disease Intervention/treatment Phase
Strabismic Deviation Other: Monovision Correction (with the help of glasses or contact lenses) Phase 1

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 20 participants
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Monovision for Treatment of Diplopia
Study Start Date : January 2009
Primary Completion Date : January 2011
Study Completion Date : January 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Eye Wear
U.S. FDA Resources

Arm Intervention/treatment
Experimental: Monovision Correctoin
Monovision correction
Other: Monovision Correction (with the help of glasses or contact lenses)

Primary Outcome Measures :
  1. Patients satisfaction with monovision was measured by standardized diplopia questionnaire and results reported in statistical terms on multiple measures tested on the questionnaire. [ Time Frame: 2 years ]
    To determine whether monovision correction was useful for the correction of small angle deviations in strabismic patients

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Strabismic Deviation less than 12 Prism Diopters

Exclusion Criteria:

  • Inability to sign informed consent

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01426672

Canada, Ontario
Edward Margolin, MD
Toronto, Ontario, Canada, M5G 1X5
Sponsors and Collaborators
Mount Sinai Hospital, Canada

Responsible Party: Edward Margolin, MD, Mount Sinai Hospital Identifier: NCT01426672     History of Changes
Other Study ID Numbers: 08-0289-EMargolin
First Posted: August 31, 2011    Key Record Dates
Last Update Posted: August 31, 2011
Last Verified: January 2011

Keywords provided by Mount Sinai Hospital, Canada:
Strabismic deviation less than 12 prism diopeters

Additional relevant MeSH terms:
Vision Disorders
Sensation Disorders
Neurologic Manifestations
Nervous System Diseases
Eye Diseases
Signs and Symptoms