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Language and Motor Skills of Preterm Infants in Pre-school Age: Diagnosis and Early Intervention (LAMOPRESCO)

This study has been completed.
Information provided by (Responsible Party):
University Hospital, Rouen Identifier:
First received: August 29, 2011
Last updated: June 2, 2015
Last verified: June 2015

The preterm children have more difficulty minor neurological developmental than the general population even without cerebral palsy. Their oral language difficulties of language and writing have been little studied. The investigators propose to study spoken language has 3 years 1/2 and stimulate or not (depending on randomization) children with phonological weaknesses notemment language. The investigators will evaluate stimulation protocol implied short and precise language in a re-education "say and do" in 20 sessions. A new evaluation of language (BILO and N-EEL), sensorimotor and cognitive constraints (KABC) will be performed at 4 years.

Early intervention on the basis of precise language before closing the window developmental (<5 years) is expected to improve as a result of language and cognitive development of preterm infants.

Condition Intervention
Disorder of Speech and Language Development Behavioral: parental stimulation according to protocol

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Official Title: Evaluation of Language and Sensorimotor Constraints of Very Premature Babies at the Age of 3 Years 1 / 2 Without Cerebral Palsy. Randomised Study of Stimulation Training Implicit in Children Vulnerable

Resource links provided by NLM:

Further study details as provided by University Hospital, Rouen:

Primary Outcome Measures:
  • parental endorsement of stimulation [ Time Frame: for at least 15 weeks ]
    stimulation every day image of the Protocol

Secondary Outcome Measures:
  • come following a speech therapy every week [ Time Frame: 15 weeks ]
    constructive working session of 30 minutes according to the protocol say and do

Enrollment: 139
Study Start Date: September 2011
Study Completion Date: February 2015
Primary Completion Date: February 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Protocol "say and do"
reeducation implicit 5 minutes every day at home and 30 minutes of speech therapy every week
Behavioral: parental stimulation according to protocol
verbal stimulation every day image of the Protocol "Dire et Faire"
Active Comparator: no stimulation "say and do" Behavioral: parental stimulation according to protocol
verbal stimulation every day image of the Protocol "Dire et Faire"

  Show Detailed Description


Ages Eligible for Study:   34 Months to 38 Months   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Premature < 32 without CP,
  • criteria of fragility BILO

Exclusion Criteria:

  • blindness,
  • deafness,
  • abnormal karyotype results in normal or pathological BILO
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01426659

University Hospital
Rouen, Haute Normandie, France, 76000
University Hospital
Caen, France, 14033
University Hospital
Grenoble, France, 38 043
University Hospital
Le Havre, France, 76600
Centre Jacques Cartier
St Brieuc, France, 22070
University Hospital
Tours, France, 37000
Sponsors and Collaborators
University Hospital, Rouen
Principal Investigator: A Charollais UH Rouen
  More Information

Responsible Party: University Hospital, Rouen Identifier: NCT01426659     History of Changes
Other Study ID Numbers: 2010/089/HP
Study First Received: August 29, 2011
Last Updated: June 2, 2015

Keywords provided by University Hospital, Rouen:
early development (< 5 years)

Additional relevant MeSH terms:
Speech Disorders
Language Disorders
Communication Disorders
Neurobehavioral Manifestations
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms processed this record on August 18, 2017