Effect of Moderate Alcohol Consumption on Postprandial Mood
|ClinicalTrials.gov Identifier: NCT01426022|
Recruitment Status : Completed
First Posted : August 30, 2011
Last Update Posted : October 18, 2012
Rationale: Food choice is influenced by postprandial mood; the feelings of well-being after a meal. Postprandial mood can be measured by subjective responses. Physiological responses may play an important role in the generation of postprandial mood. However, the relationship between subjective and physiological responses after a meal is not clear yet. To investigate this relationship, moderate alcohol consumption will be used as a mood modulator, because of its well-studied effects on mood. Postprandial mood depends on the current mood state. Therefore the investigators will manipulate the current mood state by changing the ambiance to measure the influence of moderate alcohol consumption with a meal on postprandial mood in a pleasant or unpleasant ambiance.
Objective: To determine whether moderate alcohol consumption with a meal in different ambiances affects postprandial mood, evaluated by subjective and physiological parameters.
Study design: Randomized, placebo-controlled, single-blind, cross-over trial
Study population: 28 apparently healthy, normal weight (BMI 18.5-27 kg/m2) women (18-45 y), taking oral contraceptives.
Intervention: 4 times having dinner at TNO Zeist with either 3 glasses of sparkling white wine (~30g alcohol) or alcohol-free sparkling white wine in either a pleasant or unpleasant meal ambiance.
Hypothesis: It is hypothesized that moderate alcohol consumption with a meal in different ambiances changes the response of subjective and physiological parameters of mood.
- Ho: there is no effect of alcohol consumption and ambiance on mood
- H1: there is an effect of alcohol consumption and ambiance on mood
|Condition or disease||Intervention/treatment||Phase|
|Mood Swings||Other: Nutrition Behavioral: mood manipulation||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||28 participants|
|Intervention Model:||Crossover Assignment|
|Primary Purpose:||Basic Science|
|Official Title:||The Effect of Moderate Alcohol Consumption With a Meal in Different Ambiances on Postprandial Mood, Evaluated by Subjective and Physiological Responses|
|Study Start Date :||October 2011|
|Actual Primary Completion Date :||December 2011|
|Actual Study Completion Date :||December 2011|
Placebo Comparator: Alcohol
Moderate alcohol consumption with dinner (3 glasses of sparkling white wine, containing ca. 30 g alcohol)
Behavioral: mood manipulation
Mood will be manipulated by changing the ambiance in either a pleasant or unpleasant way.
- Profile of mood states (POMS) [ Time Frame: 5 times during study day, 4 study days (total 20x) ]Difference between the change in the score of the 6 items of the POMS (after consumption of either white wine or alcohol free white wine with a meal in either a positive or negative ambiance. POMS will be measured before consumption, and 30min, 60min, 90min and 150min after consumption.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01426022
|Zeist, Utrecht, Netherlands, 3704|
|Principal Investigator:||Henk Hendriks, PhD||TNO|