Liposomal Lidocaine Gel for Oral Topical Anesthesia
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01425840|
Recruitment Status : Completed
First Posted : August 30, 2011
Last Update Posted : August 30, 2011
|Condition or disease||Intervention/treatment||Phase|
|Anesthesia||Drug: Lidocaine||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||40 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Triple (Participant, Care Provider, Investigator)|
|Primary Purpose:||Health Services Research|
|Official Title:||Efficacy of Liposome Lidocaine Gel for Topical Anesthesia in the Palatal Mucosa|
|Study Start Date :||March 2008|
|Actual Primary Completion Date :||November 2008|
|Actual Study Completion Date :||March 2009|
Experimental: Liposomal lidocaine, topical anesthesia
Efficacy of Liposomal lidocaine in topical anesthesia.
100 mg of the following formulations: Liposome-encapsulated 2,5% and 5% lidocaine gel, liposome placebo gel and 2.5% lidocaine and 2.5% prilocaine cream were applied once during 5 minutes.
Other Name: Topical anesthesia in the palatal mucosa
- The efficacy of topical anesthetics on the oral mucosa. [ Time Frame: 10 seconds ]The topical formulations were kept in the palatal mucosa during 2 min. The efficacy of the topical formulations was assessed after a pinprick and a local anesthetic injection on the application site.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01425840
|Piracicaba Dental School|
|Piracicaba, São Paulo, Brazil, 13414903|