Liposomal Lidocaine Gel for Oral Topical Anesthesia
|ClinicalTrials.gov Identifier: NCT01425840|
Recruitment Status : Completed
First Posted : August 30, 2011
Last Update Posted : August 30, 2011
|Condition or disease||Intervention/treatment||Phase|
|Anesthesia||Drug: Lidocaine||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||40 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Triple (Participant, Care Provider, Investigator)|
|Primary Purpose:||Health Services Research|
|Official Title:||Efficacy of Liposome Lidocaine Gel for Topical Anesthesia in the Palatal Mucosa|
|Study Start Date :||March 2008|
|Primary Completion Date :||November 2008|
|Study Completion Date :||March 2009|
Experimental: Liposomal lidocaine, topical anesthesia
Efficacy of Liposomal lidocaine in topical anesthesia.
100 mg of the following formulations: Liposome-encapsulated 2,5% and 5% lidocaine gel, liposome placebo gel and 2.5% lidocaine and 2.5% prilocaine cream were applied once during 5 minutes.
Other Name: Topical anesthesia in the palatal mucosa
- The efficacy of topical anesthetics on the oral mucosa. [ Time Frame: 10 seconds ]The topical formulations were kept in the palatal mucosa during 2 min. The efficacy of the topical formulations was assessed after a pinprick and a local anesthetic injection on the application site.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01425840
|Piracicaba Dental School|
|Piracicaba, São Paulo, Brazil, 13414903|