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The Effect of a Diabetic- and a Kidney-like Environment on Gene and Protein Expression in Cultured EC and SMC

This study is currently recruiting participants. (see Contacts and Locations)
Verified March 2016 by Meir Medical Center
Information provided by (Responsible Party):
Meir Medical Center Identifier:
First received: August 24, 2011
Last updated: March 15, 2016
Last verified: March 2016
This research is NOT part of an interventional trial, however the investigators use umbilical cord after birth for isolating endothelial and smooth muscle cells for academic research.

Endothelial Dysfunction
Disorder of Smooth Muscle

Study Type: Observational
Official Title: The Effect of a Diabetic- and a Kidney-like Environment on Gene and Protein Expression in Mono- and Co-cultured Endothelial and Smooth Muscle Cells

Resource links provided by NLM:

Further study details as provided by Meir Medical Center:

Primary Outcome Measures:
  • The effect of a Diabetic- and a Kidney-like environment on gene and protein expression in mono- and co-cultured endothelial and smooth muscle cells [ Time Frame: one year ]

Estimated Enrollment: 20
Study Start Date: February 2013
Estimated Study Completion Date: June 2018
Estimated Primary Completion Date: June 2017 (Final data collection date for primary outcome measure)
Detailed Description:
Isolation and culturing of endothelial and smooth muscle muscles for academic research

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Women after normal birth

Inclusion Criteria:

  • normal pregnancy

Exclusion Criteria:

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01423279

Laboratory of Renal Physiology, Meir Medical Center , Recruiting
Kfar Saba, Israel
Contact: Tali Zitman-Gal, PhD    +972-9-7472401   
Principal Investigator: Tali Zitman-Gal, PhD         
Sponsors and Collaborators
Meir Medical Center
Study Director: Sydney Benchetrit, MD Nephrology dept. Meir Medical Center, Kfar Saba , Israel