The Effect of a Diabetic- and a Kidney-like Environment on Gene and Protein Expression in Cultured EC and SMC

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Meir Medical Center Identifier:
First received: August 24, 2011
Last updated: September 10, 2014
Last verified: February 2013

This research is NOT part of an interventional trial, however the investigators use umbilical cord after birth for isolating endothelial and smooth muscle cells for academic research.

Endothelial Dysfunction
Disorder of Smooth Muscle

Study Type: Observational
Official Title: The Effect of a Diabetic- and a Kidney-like Environment on Gene and Protein Expression in Mono- and Co-cultured Endothelial and Smooth Muscle Cells

Resource links provided by NLM:

Further study details as provided by Meir Medical Center:

Primary Outcome Measures:
  • The effect of a Diabetic- and a Kidney-like environment on gene and protein expression in mono- and co-cultured endothelial and smooth muscle cells [ Time Frame: one year ] [ Designated as safety issue: No ]

Estimated Enrollment: 20
Study Start Date: February 2013
Estimated Study Completion Date: August 2015
Estimated Primary Completion Date: April 2015 (Final data collection date for primary outcome measure)
Detailed Description:

Isolation and culturing of endothelial and smooth muscle muscles for academic research


Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

Women after normal birth


Inclusion Criteria:

  • normal pregnancy

Exclusion Criteria:


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Please refer to this study by its identifier: NCT01423279

Laboratory of Renal Physiology, Meir Medical Center ,
Kfar Saba, Israel
Sponsors and Collaborators
Meir Medical Center
Study Director: Sydney Benchetrit, MD Nephrology dept. Meir Medical Center, Kfar Saba , Israel