Chronic Obstructive Pulmonary Disease and Pulmonary Hypertension: Prevalence and Quality of Life
The purpose of this study is to determine the prevalence of pulmonary hypertension (PH) among patients suffering from Chronic Obstructive Pulmonary Disease (COPD) and to assess the quality of life in those patients with concomitant PH compared to COPD patients without PH and those only suffering from pulmonary arterial hypertension (PAH) respectively.
Pulmonary Disease, Chronic Obstructive
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Chronisch Obstruktive Lungenerkrankung Und Pulmonale Hypertonie: Prävalenz Und Lebensqualität|
- Prevalence of PH [ Time Frame: At baseline ] [ Designated as safety issue: No ]Prevalence of PH as defined by ESC/ERS guidelines (mean pulmonary arterial pressure ≥25 mmHg, assessed by right-heart catheterization) among the subgroup of COPD GOLD III and IV patients.
- Quality of life [ Time Frame: One year ] [ Designated as safety issue: No ]Explorative data analysis to assess correlation between quality of life and PH, by comparison of COPD patients with and without PH and a reference group of patients with only PAH.
|Study Start Date:||August 2011|
|Study Completion Date:||January 2015|
|Primary Completion Date:||January 2015 (Final data collection date for primary outcome measure)|
COPD with PH
COPD patients with confirmed diagnosis of PH.
COPD without PH
COPD patients without confirmed diagnosis of PH
PAH without COPD
PAH patients who do not suffer from COPD
Please refer to this study by its ClinicalTrials.gov identifier: NCT01423071
|Bethanien Hospital, Clinic for Pneumology and Allergology, Center for Sleep Medicine and Respiratory Care, Institute for Pneumology at the University Witten/Herdecke|
|Solingen, NRW, Germany, 42699|
|Principal Investigator:||Winfried J Randerath, Prof. Dr. med.||Wissenschaftliches Institut Bethanien e.V|