Alzheimer's Disease Core Center (ADCC)
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|ClinicalTrials.gov Identifier: NCT01421420|
Recruitment Status : Recruiting
First Posted : August 22, 2011
Last Update Posted : June 12, 2015
The main objective of this research project is to provide a comprehensive clinical database of patients with Alzheimer's disease (AD) and other forms of dementia, individuals with mild cognitive impairment (MCI), and age-matched normal controls. The study will also attempt to identify cognitively normal individuals at genetically defined risk for Alzheimer's disease through genetic screening.
All participants are seen annually. Autopsies to establish diagnoses in patients with dementia, patients with mild MCI, and cognitively normal elderly control subjects will also be conducted.
|Condition or disease|
|Alzheimer's Disease Mild Cognitive Impairment Age-Related Memory Disorders|
|Study Type :||Observational|
|Estimated Enrollment :||900 participants|
|Official Title:||Arizona Alzheimer's Disease Core Center|
|Study Start Date :||July 2001|
|Estimated Primary Completion Date :||December 2024|
|Estimated Study Completion Date :||July 2025|
|Mild Cognitive Impairment|
|Other forms of Dementia, not AD|
|Normal Elderly Individuals|
- Neuropsychological Test Scores [ Time Frame: Up to 20 years ]Cognitive function will be evaluated on a yearly basis using a battery of neuropsychological tests, which will then be scored and normed according to established guidelines.
- Neurological Exam [ Time Frame: Up to 20 Years ]A thorough neurological exam will be performed once per year to evaluate neurological function.
- Brain Tissue [ Time Frame: From date of entry until date of death assessed up to 20 years ]A brain autopsy will be performed upon the participant's death to establish histological diagnosis.
Biospecimen Retention: Samples With DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01421420
|United States, Arizona|
|University of Arizona, University Medical Center||Recruiting|
|Tucson, Arizona, United States, 85724|
|Contact: Kim Corley, B.A. 520-626-3746 firstname.lastname@example.org|
|Principal Investigator: Steven Z Rapcsak, M.D.|
|Principal Investigator:||Steven Z Rapcsak, M.D.||University of Arizona|