Swallowing and Breathing Exercises for Dysphagia in Parkinson Disease
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ClinicalTrials.gov Identifier: NCT01420796 |
Recruitment Status
:
Completed
First Posted
: August 22, 2011
Last Update Posted
: April 27, 2017
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Condition or disease | Intervention/treatment | Phase |
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Parkinson Disease Dysphagia | Other: Swallowing exercise Other: Breathing Exercises Other: Swallowing and breathing exercises | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 38 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Intervention Model Description: | 3 arms were designed to evaluate the effect of swallowing and breathing exercises to dysphagia in PD patients. The groups were allocated randomly in A) swallowing exercises; b) Breathing exercises or C) Swallowing and breathing exercises |
Masking: | Single (Outcomes Assessor) |
Primary Purpose: | Treatment |
Official Title: | Effect of Oral Motor Exercises and Breathing Exercises for Dysphagia in Parkinson Disease: Randomized Clinical Trial |
Actual Study Start Date : | November 2013 |
Actual Primary Completion Date : | December 15, 2016 |
Actual Study Completion Date : | December 15, 2016 |

Arm | Intervention/treatment |
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Experimental: Swallowing and breathing exercises
This group will perform both swallowing and breathing exercises for five weeks.
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Other: Swallowing and breathing exercises
For five weeks, patients will perform swallowing and breathing exercises that follow: expiratory muscle training and sustained vowel phonation of /a/, pushing plosive phonemes /pa/, /ta/, /ka/ in a forceful manner, suction of wet gauze, swallowing with tongue hold and modified supraglottic maneuver, in ten repetitions, ascending and descending gliding phonation of vowel /a/ and /u/, five repetitions of each vowel, and tongue rotation in oral vestibule, 3 series of 5 repetitions to each side.
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Experimental: Swallowing exercises
This exercises aim to increase strength and range of motion of mouth, larynx and pharynx structures. All patients will perform sustained vowel phonation of /a/, pushing plosive phonemes /pa/, /ta/, /ka/ in a forceful manner, suction of wet gauze, swallowing with tongue hold and modified supraglottic maneuver, in ten repetitions, ascending and descending gliding phonation of vowel /a/ and /u/, five repetitions of each vowel, and tongue rotation in oral vestibule, 3 series of 5 repetitions to each side.
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Other: Swallowing exercise
Patients will perform oral motor exercises for swallowing muscles for five weeks, four days a week. This exercises aim to increase strength and range of motion of mouth, larynx and pharynx structures. All patients will make sustained vowel phonation of /a/, pushing plosive phonemes /pa/, /ta/, /ka/ in a forceful manner, suction of wet gauze, swallowing with tongue hold and modified supraglottic maneuver, in ten repetitions, ascending and descending gliding phonation of vowel /a/ and /u/, five repetitions of each vowel, and tongue rotation in oral vestibule, 3 series of 5 repetitions to each side. |
Experimental: Breathing exercises
Expiratory Muscle Training will be performed with Threshold® (Respironics HealthScan, Inc, Cedar Grove, Nova Iorque, EUA).
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Other: Breathing Exercises
Patients will perform expiratory muscle training. Initial load will be 30% of maximal expiratory pressure which will increase until 75%. This load will be keep until end of training. Patients will made the exercises for 30 minutes with three minutes of training and two of rest.
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- Swallowing dynamics [ Time Frame: five weeks ]Swallowing dynamics will be evaluated through videofluoroscopy of swallowing and electromyography.
- Vocal and speech measures [ Time Frame: five weeks ]After recording a sample of speech, aerodynamics measures will be extracted by Aeroview Plus software and measures of test results electroglottography will be assessed on EG2 - PCX equipment.
- Breathing measures [ Time Frame: five weeks ]Spirometry will be made in KOKO® (software PDS Instrumentation, Inc., Louisville, Colorado, EUA), following American Thoracic Society protocol.

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Ages Eligible for Study: | Child, Adult, Senior |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Parkinson's disease diagnosed following UKPDS Criteria
- Complaints and symptoms of dysphagia
- Dopaminergic treatment
Exclusion Criteria:
- Cranial trauma
- Severe heart disease
- Others neurologic disease
- Psychiatric diseases
- Therapy for swallowing or breathing in the last 3 months

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01420796
Brazil | |
Division of Neurology and Epidemiology | |
Salvador, Bahia, Brazil |
Principal Investigator: | Ana Caline N. da Costa, Phd | DINEP/UFBA |
Responsible Party: | Natalie Argolo Pereira Ponte, PhD, Federal University of Bahia |
ClinicalTrials.gov Identifier: | NCT01420796 History of Changes |
Other Study ID Numbers: |
96/10 |
First Posted: | August 22, 2011 Key Record Dates |
Last Update Posted: | April 27, 2017 |
Last Verified: | April 2017 |
Keywords provided by Natalie Argolo Pereira Ponte, Federal University of Bahia:
Parkinson's disease dysphagia swallowing treatment |
Additional relevant MeSH terms:
Parkinson Disease Deglutition Disorders Parkinsonian Disorders Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Nervous System Diseases Movement Disorders Neurodegenerative Diseases |
Esophageal Diseases Gastrointestinal Diseases Digestive System Diseases Pharyngeal Diseases Otorhinolaryngologic Diseases Menthol Antipruritics Dermatologic Agents |