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Effects of Unilateral WBV on Muscleactivity of Contralateral Hip Adductor (WBV-BM)

This study has been completed.
Information provided by (Responsible Party):
Ilhan Karacan, Clinical Associated Professor, Bagcilar Training and Research Hospital Identifier:
First received: August 17, 2011
Last updated: May 6, 2013
Last verified: May 2013

The aim of this study is to investigate effects of femur exposed to unilateral vibration on the rest muscle electrical activity of contralateral hip adductors and contralateral soleus H-reflex in young adult men.

This study hypothesize that femur exposed to unilateral vibration may affect the rest muscle electrical activity of contralateral hip adductors. Vibration can effectively enhance muscle strength and power. Previous studies have shown that vibration increases muscle electromyographic (EMG) activity. It has been showed that bone has an effect on the increase in muscle EMG activity caused by vibration in healthy young adults in a study. In this study, it was reported that vibrations-induced increases in muscle electrical activity of flexor carpi radialis (FCR) was related to ultradistal radius bone mineral content (BMC) and the FCR H-reflex was suppressed or depressed during vibration. This findings were reported to support the assumption that the bone exposed to cyclic mechanical loading may neuronally regulate muscle activity.

Condition Intervention
Bone Mass
Effects of Vibration
Other: Whole-body vibration

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Double Blind (Participant, Investigator)
Primary Purpose: Basic Science
Official Title: The Effects Of Femur On The Resting Myoelectrical Activity Of Contralateral Adductor Muscle During Unilateral Lower Extremity Vibration: Bone Myoregulation Reflex

Further study details as provided by Ilhan Karacan, Clinical Associated Professor, Bagcilar Training and Research Hospital:

Primary Outcome Measures:
  • Vibration-induced contralateral muscle electrical activity [ Time Frame: 3 month ]

Enrollment: 20
Study Start Date: March 2011
Study Completion Date: December 2012
Primary Completion Date: November 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Whole-body vibration
whole body vibration will be applied the right lower limb.
Other: Whole-body vibration
Frequency: 40 Hz, vibration amplitude: 2 mm, duration: 60 sec
Other Name: Cyclic mechanical loading

Detailed Description:

A total of 20 voluntaries are planned to include in this study.

Vibration will be applied the right lower extremity by whole-body vibration (PowerPlate Pro). Cases will stand on vibration plate. WBV will be applied at a frequency of 40 Hz and amplitude of 2 mm for 60 seconds. WBV will be applied one session only.

The rest muscle electrical activity of ipsilateral and contralateral hip adductor muscles at rest will be measured by PowerLab (data acquisition system, ADInstruments, Australia) device.The rest-EMGrms will be measured at before and during vibration. We also evaluate a change in contralateral soleus H reflex during vibration.

Effects of bone on the rest muscle electrical activity will be assessed by hip bone mineral density, bone mineral content and serum sclerostin level. The right hip bone mineral density (BMD) and BMC will be evaluated by bone densitometer (Norland). Plasma sclerostin level will be measured by using Human Sclerostin ELISA kıt before and after vibration.


Ages Eligible for Study:   20 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Age: 20-40 yrs
  • Gender: Male
  • Volunteer
  • Healthy status: Patients having hypoesthesia in his leg and Healthy subjects
  • Dominant hand:Right-handed

Exclusion Criteria:

  • Bone diseases (osteoporosis, osteomalacia, paget's disease, neoplasm, etc),
  • Systemic diseases (cardiovascular, endocrine, infections etc),
  • Myopathy-tendinopathy
  • Lower limb joint disease
  • Vertigo
  • Obesity (BMI >30 kg/m2)
  • Professional sportsman
  • Male doing regular sports activities
  • Skin disease in lower limb
  • Non-cooperative subject
  • Hemolysis of blood sample
  Contacts and Locations
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Please refer to this study by its identifier: NCT01419782

Bagcilar Training & Research Hospital
Istanbul, Turkey
Sponsors and Collaborators
Bagcilar Training and Research Hospital
Principal Investigator: ILHAN KARACAN, MD Bagcilar Training & Research Hospital
  More Information

Responsible Party: Ilhan Karacan, Clinical Associated Professor, ILHAN KARACAN, Bagcilar Training and Research Hospital Identifier: NCT01419782     History of Changes
Other Study ID Numbers: BEAH FTR-5
Study First Received: August 17, 2011
Last Updated: May 6, 2013

Keywords provided by Ilhan Karacan, Clinical Associated Professor, Bagcilar Training and Research Hospital:
rest muscle electrical activity
whole-body vibration
sclerostin processed this record on May 25, 2017