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Effect of Transversus Abdominis Plane (TAP) Block After Laparoscopic Colon Surgery

This study has been completed.
Information provided by (Responsible Party):
Copenhagen University Hospital at Herlev Identifier:
First received: June 9, 2011
Last updated: August 21, 2013
Last verified: August 2013
The purpose of this study is to investigate the effectiveness of Transversus Abdominis Plane (TAP) block as a part of a multimodal postoperative pain management after laparoscopic surgery on colon.

Condition Intervention Phase
Laparoscopic Colon Surgery
Procedure: Transversus abdominis plane (TAP) block
Procedure: Placebo TAP block
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Effect of Transversus Abdominis Plane (TAP) Block as Postoperative Pain Management After Laparoscopic Colon Surgery

Further study details as provided by Copenhagen University Hospital at Herlev:

Primary Outcome Measures:
  • Pain during cough [ Time Frame: 6 hours ]
    VAS-pain score

Secondary Outcome Measures:
  • Pain during rest [ Time Frame: 1,2,4,6,12 and 24 hours ]
    VAS-pain score at rest

  • Total opioid consumption [ Time Frame: 0-24 hours ]
    Opioid consumption via PCA-pump.

  • Postoperative nausea and vomiting [ Time Frame: 1,2,4,6,12,18 and 24 hours ]
    Nausea score 0-3 No. of vomits

Enrollment: 80
Study Start Date: August 2010
Study Completion Date: July 2013
Primary Completion Date: February 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Transversus abdominis plane (TAP) block
Transversus abdominis plane (TAP) block with ropivacaine
Procedure: Transversus abdominis plane (TAP) block
Bilateral UL-guided TAP block with 20 ml of ropivacaine 0,5%
Other Name: Naropin
Placebo Comparator: Block with saline
Bilateral placement of 20 ml of saline 0,9% in the transversus abdominis plane
Procedure: Placebo TAP block
Bilateral placement of 20 ml of saline 0,9% in the transversus abdominis plane
Other Name: Placebo block


Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Age 18 - 80
  • BMI 18 - 40
  • ASA 1 - 3
  • Written consent
  • Can cooperate

Exclusion Criteria:

  • Mb Chron and Collitis Ulcerosa
  • Drug and alcohol abuse
  • Pregnancy
  • Consumption of opioids
  • Drug allergy
  Contacts and Locations
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Please refer to this study by its identifier: NCT01418144

Herlev University Hospital, Department of anaesthesia
Copenhagen, Herlev, Denmark, 2730
Sponsors and Collaborators
Copenhagen University Hospital at Herlev
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Copenhagen University Hospital at Herlev Identifier: NCT01418144     History of Changes
Other Study ID Numbers: SM1-HT-2010
Study First Received: June 9, 2011
Last Updated: August 21, 2013 processed this record on April 28, 2017