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Adjunctive Local Application of Lidocaine During Scleral Buckling Under General Anesthesia

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2010 by Isfahan University of Medical Sciences.
Recruitment status was:  Recruiting
Information provided by:
Isfahan University of Medical Sciences Identifier:
First received: August 9, 2011
Last updated: August 15, 2011
Last verified: January 2010
The purpose of this study is to evaluate the effect of topical lidocaine in scleral buckling surgery.

Condition Intervention Phase
Retinal Detachment Drug: lidocaine Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Investigator)
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by Isfahan University of Medical Sciences:

Primary Outcome Measures:
  • intraoperative heart rate measurement [ Time Frame: 6 month ]
  • decrease in pain and nausea,vomiting after surgery [ Time Frame: 6 month ]
  • decrease in ocr after application of topical lidocaine [ Time Frame: 6 month ]
  • postoperative nausea and vommitting [ Time Frame: 6 month ]
  • postoperative pain [ Time Frame: 6 month ]

Estimated Enrollment: 30
Study Start Date: January 2010
Estimated Study Completion Date: September 2011
Primary Completion Date: August 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: lidocaine Drug: lidocaine
to evaluate the effect of lidocaine on oculocardiac reflex during the surgery


Ages Eligible for Study:   20 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Retinal detachment
  • Retinal tear less than 3 hour clock

Exclusion Criteria:

  • Vitreous hemorrhage
  • Proliferative vitreoretinopathy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01417572

Contact: Amin Masjedi, MD +983112211915

Iran, Islamic Republic of
Isfahan University of Medical Sciences Recruiting
Isfahan, Iran, Islamic Republic of, 7864329800
Contact: amin masjedi, MD    +983112211915   
Principal Investigator: Amin Masjedi, MD         
Sponsors and Collaborators
Isfahan University of Medical Sciences
  More Information

Responsible Party: isfahan university of medical sciences Identifier: NCT01417572     History of Changes
Other Study ID Numbers: 199
Study First Received: August 9, 2011
Last Updated: August 15, 2011

Additional relevant MeSH terms:
Retinal Detachment
Retinal Diseases
Eye Diseases
Anesthetics, Local
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Anti-Arrhythmia Agents
Voltage-Gated Sodium Channel Blockers
Sodium Channel Blockers
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action processed this record on September 21, 2017