ClinicalTrials.gov
ClinicalTrials.gov Menu

Changes in the Permeability of the Blood Brain Barrier and Intestinal Barrier in Humans During Conditions of Stress and Immune Activation: in Vivo Studies

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01417416
Recruitment Status : Completed
First Posted : August 16, 2011
Last Update Posted : August 16, 2011
Sponsor:
Information provided by:
National University Hospital, Singapore

Brief Summary:
The relevance of BBB and IB permeability changes as a major precipitating cause for cognitive and digestive dysfunction in the military stress setting.

Condition or disease
Combat Training Stress

Study Type : Observational
Observational Model: Cohort
Time Perspective: Prospective

Group/Cohort
with combat training stress
without combat training stress




Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Male
Sampling Method:   Probability Sample
Study Population
Healthy male troops during combat training
Criteria

Inclusion Criteria:

  • Healthy male troops (aged 18-50 yrs) scheduled to be engaged in a protracted multi-day stressful field exercises.

Exclusion Criteria:

  • Significantly systemic disease, including cardiovascular, psychiatric, neurological (including polyneuropathies) and endocrine disease including diabetes mellitus.
  • No written informed consent obtained from subject.

ClinicalTrials.gov Identifier: NCT01417416     History of Changes
Other Study ID Numbers: C/08/236
DSOCL08210 ( Other Grant/Funding Number: DSTA Singapore )
First Posted: August 16, 2011    Key Record Dates
Last Update Posted: August 16, 2011
Last Verified: February 2009