Thromboelastography to Assess Age-Related Coagulation Differences in Patients Undergoing Cesarean Delivery
The purpose of the study is to assess potential age-related differences on coagulation profile of patients undergoing Cesarean Section, using thromboelastography (TEG). The investigators will compare coagulation data collected from the study to assess potential differences in coagulation parameters for the following age groups: (i) women less than 35 yrs (ii) women 35 yrs or older.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Thromboelastography to Assess Age-Related Coagulation Differences in Patients Undergoing Elective Cesarean Delivery.|
- Thromboelastography parameters [ Time Frame: 3 days ] [ Designated as safety issue: No ]
Thromboelastography parameters include:
Reaction (r) time Clot Formation (k) time Alpha Angle Maximum Amplitude (MA) Time to maximum rate of thrombus generation (Tmax) Maximum rate of thrombus generation (MRTG) Total Thrombus generated (TTG)
- laboratory coagulation parameters [ Time Frame: 3 days ] [ Designated as safety issue: No ]
- Prothrombin time
- Activated partial thromboplastin time
- Fibrinogen level.
|Study Start Date:||October 2010|
|Study Completion Date:||November 2012|
|Primary Completion Date:||April 2012 (Final data collection date for primary outcome measure)|
Elective Cesarean delivery, age <35 yrs
Women undergoing elective cesarean delivery with a spinal anesthetic who are less than 35 y of age (at the time of delivery).
Elective Cesarean delivery, age =>35 yrs
Women undergoing elective Cesarean delivery with a spinal anesthetic who are => 35 yrs of age (at the time of delivery).
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01416454
|United States, California|
|Stanford University School of Medicine|
|Stanford, California, United States, 94305|
|Principal Investigator:||Alex James Butwick||Stanford University|