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Tibial Nerve Versus Sciatic Nerve Block

This study has been completed.
Information provided by (Responsible Party):
Saint Francis Care Identifier:
First received: August 1, 2011
Last updated: March 17, 2015
Last verified: August 2011
The purpose of this study is to analyse the ability to selectively block the posterior tibial nerve sparing the function of the common peritoneal nerve. To assess the efficacy of blocking the posterior tibial nerve will give the same post-operative pain relief after total knee surgery compared to a sciatic nerve block.

Condition Intervention
Post Operative Analgesia Procedure: Selective Tibial Nerve block Procedure: Sciatic Nerve Block

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Care Provider)
Primary Purpose: Treatment
Official Title: Selective Tibial Nerve Block vs Popliteal Sciatic Nerve Block in Patients Having Total Knee Arthroplasty

Further study details as provided by Saint Francis Care:

Primary Outcome Measures:
  • To assess if selectively blocking only the tibial nerve component of the sciatic nerve will prevent foot drop. [ Time Frame: Upon emergence from general anesthesia and up to 48 hours in the recovery room. ]
    Measure frequency of foot drop in two groups and compare results.

Secondary Outcome Measures:
  • To assess if levels of pain and analgesic requirements are similar between the two groups. [ Time Frame: 24 hours after total knee replacement surgery. ]
    Administer pain scale and monitor use of analgesics to compare levels two groups.

Enrollment: 80
Study Start Date: March 2009
Study Completion Date: December 2010
Primary Completion Date: March 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Selective Tibial Nerve Block Procedure: Selective Tibial Nerve block
Use of selective pain block.
Active Comparator: Control: Sciatic Nerve Block Procedure: Sciatic Nerve Block
Use of Sciatic Nerve Block


Ages Eligible for Study:   18 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • total knee replacement

Exclusion Criteria:

  • History of neuralgia, diabetes, pregnancy, allergy to local anesthetic solutions
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01415193

United States, Connecticut
Saint Francis Hospital and Medical Center
Hartford, Connecticut, United States, 06105
Sponsors and Collaborators
Saint Francis Care
Principal Investigator: Sanjay Sinha, MD Saint Francis Memorial Hospital
  More Information

Responsible Party: Saint Francis Care Identifier: NCT01415193     History of Changes
Other Study ID Numbers: 09-02-002
Study First Received: August 1, 2011
Last Updated: March 17, 2015 processed this record on September 21, 2017