Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2011 by Medical University of Vienna.
Recruitment status was  Recruiting
Information provided by (Responsible Party):
Markus Zeitlinger, Medical University of Vienna Identifier:
First received: August 10, 2011
Last updated: September 5, 2011
Last verified: September 2011
The investigators will measure the pharmacokinetics of doripenem in skeletal muscle, subcutaneous adipose tissue, bronchoalveolar lavage and plasma of intubated intensive care patients.

Abdominal Infection
Urinary Tract Infection

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients

Further study details as provided by Medical University of Vienna:

Biospecimen Retention:   Samples Without DNA
plasma broncheoalvoeolar lavage microdialysates

Estimated Enrollment: 16
Study Start Date: August 2011
Estimated Study Completion Date: July 2013
Detailed Description:
Methods: microdialysis, blood sampling, bronchoalveolar lavage

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
intubated patients, intensive care

Inclusion Criteria:

  • endotracheal intubation; pneumonia or complicated abdominal infection or complicated urinary tract infection

Exclusion Criteria:

  • allergy to doripenem, hemodialysis
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01414959

Contact: markus zeitlinger, md 0043140400 ext 2981

Med. Univ. of Vienna Recruiting
Vienna, Austria, 1090
Contact: robert sauermann, md         
Contact: markus zeitligner, md         
Sponsors and Collaborators
Medical University of Vienna
Principal Investigator: Markus Zeitlinger, MD Medical Universit of Vienna
  More Information

No publications provided

Responsible Party: Markus Zeitlinger, Professor Dr., Medical University of Vienna Identifier: NCT01414959     History of Changes
Other Study ID Numbers: Dori_MD_ICU
Study First Received: August 10, 2011
Last Updated: September 5, 2011
Health Authority: Austria: Ethikkommission

Keywords provided by Medical University of Vienna:
intensive care patient
(please change wording as you like!)

Additional relevant MeSH terms:
Intraabdominal Infections
Urinary Tract Infections
Urologic Diseases processed this record on November 24, 2015