In Utero Capacity Formation and Socio-economic Outcomes (CDS)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01412580
Recruitment Status : Completed
First Posted : August 9, 2011
Last Update Posted : March 27, 2017
Information provided by (Responsible Party):
Harvard University

Brief Summary:
Because of the high returns of schooling in developing countries, policymakers pay a lot of attention to increasing school access. But if the mother is deficient in key micronutrients, brain development can biologically constrain children's demand for education. To execute this strategy, the investigators collect cohort observational data on a previous randomized controlled trial with micronutrient supplements offered to HIV-negative pregnant women in Dar es Salaam, Tanzania, between 2001 to 2003.

Condition or disease Intervention/treatment
Folic Acid Deficiency Other: observational follow-up

Detailed Description:
This is a cohort study which collected follow-up observational data on households which were offered micronutrient supplements. The followup study outcomes include various socio-economic household characteristics and parental post-natal behaviors.

Study Type : Observational
Actual Enrollment : 4000 participants
Observational Model: Family-Based
Time Perspective: Prospective
Official Title: The Contribution of Health in Utero to Capacity Formation, Education and Economic Outcomes: Experimental Evidence From Tanzania
Study Start Date : April 2002
Primary Completion Date : September 2012
Study Completion Date : September 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Folic Acid
U.S. FDA Resources

Group/Cohort Intervention/treatment
observational followup
This was an observational follow-up to a larger study in which treatment group was given 20 mg of vitamin B1, 20 mg of vitamin B2, 25 mg of vitamin B6, 100 mg of niacin, 50 μg of vitamin B12, 500 mg of vitamin C, 30 mg of vitamin E, and 0.8 mg of folic acid
Other: observational follow-up
observational follow-up

Primary Outcome Measures :
  1. Children's Cognitive Development [ Time Frame: During 2011-2012 (1 year) ]
  2. Children's Health [ Time Frame: During 2011-2012 (1 year) ]
    BMI, Disease Incidence, Self-reported health

  3. Parental Postnatal Investment Behavior [ Time Frame: During 2011-2012 (1 year) ]
    Outcomes on parental care: care, cognitive stimulation, within-household time and money allocation

  4. Educational Status [ Time Frame: During 2011-2012 (1 year) ]
    School attendance, Student performance (at school), Test Performance

Secondary Outcome Measures :
  1. Parental Labor Force Participation [ Time Frame: During 2011-2012 (1 year) ]
    Parent's labor force outcomes: labor status, wages, type of job

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Ages Eligible for Study:   18 Years to 49 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Individuals from a larger study and this study is an observational follow-up.
These were individuals from the larger study and this study is an observational follow-up.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01412580

Dar es Salaam, Tanzania
Sponsors and Collaborators
Harvard University
Study Director: Plamen Nikolov Harvard University

Responsible Party: Harvard University Identifier: NCT01412580     History of Changes
Other Study ID Numbers: F19899-101
First Posted: August 9, 2011    Key Record Dates
Last Update Posted: March 27, 2017
Last Verified: March 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Additional relevant MeSH terms:
Folic Acid Deficiency
Vitamin B Deficiency
Deficiency Diseases
Nutrition Disorders