Early Brain Development in Twins
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|ClinicalTrials.gov Identifier: NCT01409746|
Recruitment Status : Active, not recruiting
First Posted : August 4, 2011
Last Update Posted : April 23, 2018
|Condition or disease|
|Twin Brain Development|
|Study Type :||Observational|
|Estimated Enrollment :||600 participants|
|Official Title:||Early Brain Development in Twins|
|Study Start Date :||April 2004|
|Estimated Primary Completion Date :||March 2020|
|Estimated Study Completion Date :||March 2020|
- Brain Gray Matter Volume [ Time Frame: Change in heritability from birth to age 6 years ]Will assess gray matter volume with MRI and use structural equation modeling to determine relative contributions of genes and environment to variation of gray matter volumes.
- Brain white matter tract integrity [ Time Frame: Change in heritability from birth to age 6 years ]Will assess white matter tract development and integrity using diffusion tensor imaging and will determine relative contributions of genes and environment ot this using twin methodology.
- Mullen composite Score [ Time Frame: 1,2,4,6 years ]Will assess genetic and environmental contributions to early cognitive development using a twin methodology
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01409746
|United States, North Carolina|
|UNC Department of Psychiatry|
|Chapel Hill, North Carolina, United States, 27599|
|Principal Investigator:||John H Gilmore, MD||University of North Carolina, Chapel Hill|