Family Focused Treatment of Pediatric Obsessive Compulsive Disorder (PFIT)
|ClinicalTrials.gov Identifier: NCT01409642|
Recruitment Status : Unknown
Verified May 2016 by Tara Peris, University of California, Los Angeles.
Recruitment status was: Recruiting
First Posted : August 4, 2011
Last Update Posted : May 13, 2016
Pediatric obsessive compulsive disorder (OCD) is a chronic, impairing condition that accrues significant concurrent and long-term risk to affected youth (Piacentini et al. 2003; Pine et al. 1998). Although a host of pharmacological and psychosocial treatments have proliferated over the past decade (Barrett et al., 2008), many youth fail torespond to treatment and many who do respond continue to exhibit lingering symptoms and impairment. Thus, there is still much to be done by way of optimizing treatment outcomes for pediatric OCD.
Increasingly, efforts to improve existing treatments have focused on aspects of the family environment that may affect treatment adherence and the maintenance of therapeutic gains. Such work suggests that parental accommodation and criticism are common characteristics of the home environment for both adults and children with OCD (Calvocoressi et al., 1999; Peris, Roblek, Langley, Chang, McCracken, & Piacentini, 2008; Van Noppen et al., 1991) and that, in adult samples, these family features are associated with poorer treatment outcome and greater risk of relapse (Amir, Freshman, & Foa, 2000; Chambless & Steketee, 1999;Leonard et al., 1993). These family-level variables are logical targets for intervention, particularly among treatment refractory groups of youth with OCD. However, they often are unaddressed in extant interventions.
The current study tests a novel intervention that specifically targets family accommodation and conflict in an effort to foster an environment that supports a graded exposure approach to treatment. The proposed treatment, Positive Family Interaction Therapy (PFIT), is composed of an innovative blend of techniques that address several potential barriers to treatment. First, the treatment is guided by the specific needs of youth with OCD and their families (e.g., accommodation, conflict). The first phase of the proposed study will involve an open case series in order to assess the utility of the PFIT protocol and feasibility of training other therapists and using the manual with a range of patient presentations. The second phase will involve a small controlled feasibility trial evaluating the extent to which recruitment, randomization, and implementation of the control condition are viable for further study. It is hypothesized that the PFIT treatment will be feasible to implement and will yield higher levels of patient satisfaction compared to treatment as usual.
|Condition or disease||Intervention/treatment||Phase|
|Obsessive-Compulsive Disorder||Behavioral: Individual Child CBT Behavioral: Positive Family Interaction Therapy||Not Applicable|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||40 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||Pilot Feasibility Trial of Positive Family Interaction Therapy|
|Study Start Date :||January 2008|
|Estimated Primary Completion Date :||December 2016|
|Estimated Study Completion Date :||December 2016|
Active Comparator: Individual Child CBT
12 sessions of individual child-focused cognitive behavior therapy with a parent component
Behavioral: Individual Child CBT
12 sessions of individual child focused cognitive behavior therapy with a parent component
Other Name: child cognitive behavior therapy
Experimental: Positive Family Interaction Therapy
12 sessions of standard individual child CBT plus six sessions of positive family interaction therapy (PFIT)
Behavioral: Positive Family Interaction Therapy
Six sessions of family-focused treatment for childhood OCD administered as an adjunct to 12 sessions of child CBTBehavioral: Positive Family Interaction Therapy
Positive Family Interaction Therapy (PFIT) is a 6-session treatment designed to be used as an adjunct to standard child CBT in cases where OCD is complicated by challenging family dynamics.
Other Name: PFIT
- OCD symptom severity on the Children's Yale Brown Obsessive Compulsive Scale (CYBOCS) [ Time Frame: Post-treatment (week 12) ]Treatment outcome will be evaluated based on decreases in total OCD symptom severity as measured by the CYBOCS.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01409642
|United States, California|
|University of California, Los Angeles||Recruiting|
|Los Angeles, California, United States, 90095|
|Contact: Tara S Peris, Ph.D. 310-794-4347 firstname.lastname@example.org|
|Principal Investigator: Tara S Peris, Ph.D.|
|Principal Investigator:||Tara S Peris, Ph.D.||University of California, Los Angeles|