Evaluation of Autonomic System Before and After Anticholinergic Treatment in Women With Overactive Bladder
|ClinicalTrials.gov Identifier: NCT01409512|
Recruitment Status : Unknown
Verified August 2011 by Rambam Health Care Campus.
Recruitment status was: Not yet recruiting
First Posted : August 4, 2011
Last Update Posted : August 4, 2011
The aim of the study is to evaluate changes in autonomic nervous system following treatment with anticholinergic medication for OAB symptoms.
Heart variability as a measure of the functioning of the autonomic nervous system will be recorded before and three months following treatment with solifenacin succinate 10 mg daily.
|Condition or disease||Intervention/treatment|
|Overactive Bladder||Procedure: ECG recording|
|Study Type :||Observational|
|Estimated Enrollment :||30 participants|
|Official Title:||Observational Study on the Effect of Anticholinergic on the Autonomic System in Women With OAB|
|Study Start Date :||September 2011|
|Estimated Primary Completion Date :||September 2013|
|Estimated Study Completion Date :||September 2013|
Women with OAB
Patients that will be diagnosed as having OAB syndrome by an urogynecologist based on their clinical symptoms (urinary urgency, with or without urinary urgency incontinence, urinary frequency or nocturia).
Procedure: ECG recording
At baseline and following 3 months on anticholinergic medications patients, ECG recording will be conducted.
Other Name: Electro cardiogram recording
- Changes in heart variability following treatment with Solifenacin succinate 10 mg [ Time Frame: 24 months ]
- Correlation between changes in clinical symptoms of OAB abd changes in heart rate variability [ Time Frame: 24 months ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01409512
|Contact: Dalia Kesner, MD||DALIAKE@clalit.org.il|
|Contact: Lior Lowenstein, MD||0502061434||Lowensteinmd@gmail.com|
|Zvolon Medical Center||Not yet recruiting|
|Haifa, Israel, 34987|
|Contact: Lior Lowenstein, MD 97248542612 LowensteinMD@gmail.com|
|Principal Investigator: Dalia Kesner, MD|
|Sub-Investigator: Lior Lowenstein, MD|
|Sub-Investigator: Eyal Goldshmith, MD|
|Sub-Investigator: Talma Rosen, RN|
|Study Chair:||Lior Lowensrtein, MD||Rambam Health Care Campus|