Study on the Effects of Exogenous Testosterone on Threat Perception and Behavioral Avoidance
|ClinicalTrials.gov Identifier: NCT01408498|
Recruitment Status : Completed
First Posted : August 3, 2011
Last Update Posted : October 16, 2012
|Condition or disease||Intervention/treatment||Phase|
|Testosterone's Effects on Threat Perception/Response||Drug: Testosterone||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||120 participants|
|Intervention Model:||Parallel Assignment|
|Primary Purpose:||Basic Science|
|Official Title:||Study on the Effects of Exogenous Testosterone on Threat Perception and Behavioral Avoidance|
|Study Start Date :||January 2012|
|Actual Primary Completion Date :||April 2012|
|Actual Study Completion Date :||April 2012|
No Intervention: Placebo Control
Control group who will not receive exogenous testosterone administration. Will act as a comparison group to the testosterone group.
Experimental: Testosterone administration group
Experimental group that will receive a single 10 g dose of 1% testosterone topical gel.
Topical administration of testosterone gel. Participants receive a one-time, single dose of 10 g of 1% testosterone gel.
Other Name: AngroGel
- Behavioral response [ Time Frame: 16 hours post testosterone administration ]Participants will be asked to give a public speech, but will be given the opportunity to postpone the speech to a future date. Postponement is considered an avoidance-oriented behavioral response to a perceived social threat.
- Physiological response [ Time Frame: 16 hours post testosterone administration ]Participants will have cortisol and cardiovascular tone tracked during the social threat protocol. Prior to, during, and after being asked, preparing, and giving a public speech, participants' physiological stress markers will be assessed.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01408498
|United States, Texas|
|Austin, Texas, United States, 78712|
|Principal Investigator:||Scott H Liening, B.A.||University of Texas at Austin|