Viability Imaging in Volumetric Angiography (VIVA 1) (VIVA 1)
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|ClinicalTrials.gov Identifier: NCT01408134|
Recruitment Status : Terminated (PI/Project director no longer at facility)
First Posted : August 3, 2011
Last Update Posted : March 29, 2013
The primary objective of this study is twofold:
- To define inter-reader variability of myocardial viability imaging within the first pass and delayed enhancement cardiac CT perfusion imaging
- To evaluate DE CT image quality using a consensus DECT protocol
|Condition or disease||Intervention/treatment||Phase|
|Myocardial Scarring||Other: DE CT||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||10 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Viability Imaging in Volumetric Angiography (VIVA 1): A Single Center Trial of the Detection of Delayed Hyperenhancement on CT Angiography|
|Study Start Date :||June 2011|
|Actual Primary Completion Date :||February 2012|
|Actual Study Completion Date :||February 2013|
- Other: DE CT
Delayed scan (per VIVA protocol): The delayed scan will be performed 10 minutes after contrast second contrast bolus complete using axial acquisition at 100 kVp. Scan length will be limited to the cardiac structures.
- Inter-reader variability of myocardial viability [ Time Frame: day One ]
To define inter-reader variability of myocardial viability imaging within the first pass and delayed enhancement cardiac CT perfusion imaging, specifically:
- Per myocardial segment binary visual estimation of the presence/absence of contrast enhancement on either a first pass or 10-minute delayed CT scan.
- Myocardial enhancement (hyper and hypo-enhancement) will be evaluated using a binary assessment for estimation of the involved myocardial segments on delayed images. Regional wall motion will be assessed qualitatively using a 4 point scale: normal, hypokinetic, akinetic, dyskinetic.
- DE CT image quality [ Time Frame: day One ]To evaluate DE CT image quality using a consensus DECT protocol
- Scan and patient factors related to the image quality [ Time Frame: day One ]The secondary endpoint will be to describe the scan and patient factors related to the image quality on myocardial CT perfusion imaging
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01408134
|United States, District of Columbia|
|Washington Hospital Center|
|Washington, District of Columbia, United States, 20010|