The Role Of Noninvasive 320-Row Multidetector Computer Tomography
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|ClinicalTrials.gov Identifier: NCT01405690|
Recruitment Status : Completed
First Posted : July 29, 2011
Last Update Posted : December 5, 2016
|Condition or disease|
|Coronary Artery Disease|
This pilot study consisting of a prospective non-randomized observational trial where a team of surgeon, anesthesiologist, and evaluator are blinded to CTCA results. We hypothesize that the preoperative use of noninvasive computer tomography, with the 320-row MDCT, to visualize the degree of coronary artery stenosis can lead to improved clinical prediction of perioperative cardiac complications.
The 320-row MDCT is based on the 64-row technology with the significant addition of a larger detector capable of scanning the heart within 1 sec or a cardiac cycle, thereby, eliminating patient-related artifacts and may produce higher image quality.13, 14 The scanning time of 5 seconds with the 320-row MDCT is significantly reduced compared to 8-10 seconds for the 64-row MDCT
|Study Type :||Observational|
|Actual Enrollment :||100 participants|
|Official Title:||A Pilot Study: The Role Of Noninvasive 320-Row Multidetector Computer Tomography Coronary Angiogram In Predicting Perioperative Cardiac Complications In Patients Referred For Noncardiac Surgery|
|Study Start Date :||September 2008|
|Actual Primary Completion Date :||June 2014|
|Actual Study Completion Date :||February 2016|
- To assess the coronary luminal stenosis for location, number of vessels involved and severity of luminal stenosis using noninvasive CTCA. [ Time Frame: CTCA 1-2 hours ]CTCA will be read by a cardiac radiologist blinded to the patients' medical/cardiac history and the results of the stress test. The cardiac radiologist will classify the severity of coronary artery disease according to number of vessels, location and degree of luminal steno-occlusive disease.
- Perioperative cardiac complications [ Time Frame: In hospital day 0-3, 30 days post surgery and one year ]Non-fatal and fatal cardiac complications will be reviewed day 0- 3 and day 30 post-surgery and one year. Patients who are discharged home will be contacted by telephone by a research assistant for post-operative follow-up. Non-fatal cardiac complications include myocardial infarction, arrythmias, electrocardiogram ischemic changes, cardiac enzymes elevation, symptoms of congestive heart failure and/or angina
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01405690
|University Heatlh Network, Mount Sinai, Toronto General Hopsital sites|
|Toronto, Ontario, Canada, M5G 2C4|
|Principal Investigator:||Eric You Ten Kong, MD PhD FRCPC||Mount Sinai Hospital, University Health Network|