Carotenoid Response to the Intake of Vegetables and Fruits
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ClinicalTrials.gov Identifier: NCT01403844 |
Recruitment Status
:
Completed
First Posted
: July 27, 2011
Last Update Posted
: September 26, 2017
|
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Resonance Raman Spectroscopy for Dietary Carotenoid Intake | Other: Carotenoid Depletion Other: Carotenoid Repletion Other: Natural Repletion | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 29 participants |
Intervention Model: | Single Group Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Basic Science |
Official Title: | Skin Carotenoid Response to Intake of Vegetables and Fruits Recommended by the Dietary Guidelines |
Actual Study Start Date : | June 2011 |
Actual Primary Completion Date : | September 2012 |
Actual Study Completion Date : | September 2012 |
Arm | Intervention/treatment |
---|---|
Skin Carotenoids
Skin carotenoids will be measured under conditions of depletion or repletion
|
Other: Carotenoid Depletion
Depletion of carotenoids using a restricted food list
Other: Carotenoid Repletion
Carotenoid repletion with provided diet based on dietary guidelines.
Other: Carotenoid Depletion
Carotenoid depletion using a restricted food list.
Other: Natural Repletion
Resumption of usual personal diet regimen. No restrictions.
|
- Serum and skin levels of carotenoids in adults fed a high carotenoid diet [ Time Frame: 28 weeks ]

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Ages Eligible for Study: | 18 Years to 65 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Men and women aged 18 - 65 years
- Weight stable (±5 lbs) for at least 2 months prior to the start of the study
- Body mass index (BMI) between 19-30 kg/m2
- Willing to refrain from the use of nicotine and dietary supplements for the duration of the study
- Willing to maintain baseline weight and physical activity levels
Exclusion Criteria:
- BMI greater than 30.
- Gastrointestinal disorders, disease, or medication that affects carotenoid absorption or storage
- Current smoker
- Allergies or intolerances to foods to be utilized in the study
- Consumption of greater than an average of 1 alcoholic drink/day for women and 2/day for men, use of nutritional/sports supplements (if unwilling to discontinue during the study)
- Pregnancy or lactating

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01403844
United States, North Dakota | |
Grand Forks Human Nutrition Research Center | |
Grand Forks, North Dakota, United States, 58203 |
Principal Investigator: | Lisa Jahns, PhD, RD | Agricultural Research Service, United States Department of Agriculture, Grand Forks Human Nutrition Research Center |
Additional Information:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Lisa Jahns, PhD, RD, USDA Grand Forks Human Nutrition Research Center |
ClinicalTrials.gov Identifier: | NCT01403844 History of Changes |
Other Study ID Numbers: |
GFHNRC022 |
First Posted: | July 27, 2011 Key Record Dates |
Last Update Posted: | September 26, 2017 |
Last Verified: | September 2017 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | No |
Keywords provided by Lisa Jahns, USDA Grand Forks Human Nutrition Research Center:
resonance Raman spectroscopy Dietary Guidelines fruits biomarkers |
carotenoids MyPlate vegetables |
Additional relevant MeSH terms:
Carotenoids Antioxidants Molecular Mechanisms of Pharmacological Action Protective Agents Physiological Effects of Drugs |