System for Measuring Non-invasive Blood Flow in the Tracheobronchial Mucosa: Validation of Reproducibility
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|ClinicalTrials.gov Identifier: NCT01402752|
Recruitment Status : Withdrawn (20131209 Regulatory authorization is currently blocked at the ANSM.)
First Posted : July 26, 2011
Last Update Posted : June 19, 2017
|Condition or disease||Intervention/treatment|
|Healthy||Biological: Blood flow to the tracheo-bronchial mucosa|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||0 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||System for Measuring Non-invasive Blood Flow in the Tracheobronchial Mucosa: Validation of Reproducibility|
|Study Start Date :||November 2013|
|Estimated Primary Completion Date :||March 2014|
|Estimated Study Completion Date :||March 2014|
Experimental: All patients
All patients included in this study according to stated inclusion and exclusion criteria.
Biological: Blood flow to the tracheo-bronchial mucosa
Measurement of blood flow to the tracheo-bronchial mucosa via differential absorption of diluted dimethyl ether tracer gas.
- The reproducibility of two measures of Qaw at a five minute interval [ Time Frame: Five minutes ]Qaw is the blood flow measured in the tracheobronchial mucosa. Qaw = VDME/(FDME*alpha*10s) where VDME is the volume of dimethyl-ether exhaled (ml), FDME is the mean concentration of dimethyl-ether (%), alpha is the Bunsen coefficient for the dissolution of dimethyl ether in tissues and blood at 37°C (i.e. 9ml/ml).
- The time necessary to complete one measure of Qaw (minutes) [ Time Frame: Day 1 ]Qaw = blood flow measured in the tracheobronchial mucosa
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01402752
|Principal Investigator:||Charles Le Merre, MD||Centre Hospitalier Universitaire de Nîmes|