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Gingival Clefts and Orthodontic Movement

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified July 2011 by Medical University of Vienna.
Recruitment status was:  Recruiting
Information provided by:
Medical University of Vienna Identifier:
First received: July 25, 2011
Last updated: May 19, 2014
Last verified: July 2011
Clefts or invaginations of the gingival tissue are a frequent finding during orthodontic space closure after extraction of a tooth. They occur in about 35% of the cases. Increased risk of developing a gingival cleft is given in the mandibular arch. A gingival invagination impairs aesthetics, orthodontic treatment and periodontal health. The aim of this prospective split-mouth designed observer blinded study is to evaluate possible differences between tooth movement in recent or in healed extraction sockets on incidence of gingival clefts. We hypothesize, that similar to the results originated from an animal study immediate movement in extraction sockets reduces incidence of gingival clefts during orthodontic space closure.

Condition Intervention
Gingival Clefts Extraction Socket Orthodontic Movement Other: time point of tooth extraction

Study Type: Interventional
Study Design: Allocation: Randomized
Masking: Single (Investigator)
Primary Purpose: Treatment
Official Title: A Prospective Split-mouth Designed Study on the Incidence of Gingival Clefts During Orthodontic Space Closure Into Recent or Healed Extraction Sockets.

Further study details as provided by Medical University of Vienna:

Primary Outcome Measures:
  • incidence of gingival clefts [ Time Frame: up to 6 months ]

Estimated Enrollment: 25
Study Start Date: July 2011
Estimated Primary Completion Date: December 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
early or late tooth extraction Other: time point of tooth extraction


Ages Eligible for Study:   10 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • extraction of both molars or premolars in the upper or lower jaw and orthodontic space closure

Exclusion Criteria:

  • periodontal status not allowing orthodontic treatment
  Contacts and Locations
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Please refer to this study by its identifier: NCT01402323

Contact: Kristina Bertl, DMD +43 664 5151194

Bernhard Gottlieb School of Dentistry, Medical University of Vienna Recruiting
Vienna, Austria, 1090
Contact: Kristina Bertl, DMD    +43 664 51515194   
Sponsors and Collaborators
Medical University of Vienna
  More Information Identifier: NCT01402323     History of Changes
Other Study ID Numbers: EK Nr 105/2011
Study First Received: July 25, 2011
Last Updated: May 19, 2014 processed this record on September 21, 2017